Renin-Angiotensin Lecture

Question 1

Aliskiren acts on which receptor?

Answer 1

renin

Question 2

How does Aliskiren work?

Answer 2

Blocks renin from converting Angiotensinogen to Ang1

Question 3

Which drug blocks renin from converting Angiotensinogen to Ang1

Answer 3

Aliskiren

Question 4

side effects of aliskiren?

Answer 4

hypotension

Question 5

Contraindications of Aliskiren?

Answer 5

Pregnancy

Question 6

Losartan acts on which kind of receptor

Answer 6

AT1 antagonist

Question 7

Blocks AT1 effects, and causes more AT2 stimulation

Answer 7

Losartan

Question 8

Losartan blocks which receptor

Answer 8

AT1

Question 9

Side effects of Losartan:

Answer 9

Takes 4-6 wks to work, do not increases dose if results are not immediate

Question 10

Contraindication of Losartan

Answer 10

pregnancy

Question 11

Captopril works on receptor how?

Answer 11

ACE inhibitor

Question 12

3 ACE inhbitors

Answer 12

Captopril
Enalapril
Lisinopril

Question 13

Block ACE from converting Ang1 to Ang2, and from catabolzing bradykinin.

Answer 13

ACE inhibitors

Question 14

Mechanism of Captopril

Answer 14

Block ACE from converting Ang1 to Ang2, and from catabolzing bradykinin.

Question 15

Mechanism of Enalapril

Answer 15

Block ACE from converting Ang1 to Ang2, and from catabolzing bradykinin.

Question 16

Mechanism of Lisinopril

Answer 16

Block ACE from converting Ang1 to Ang2, and from catabolzing bradykinin.

Question 17

Side effects of ACE inhibitors

Answer 17

Angioedema, Hyperkalemia (as ANG2 stimulates Aldosterone). Cough (bradykinin)

Question 18

Side effects of Captopril, Enalapril, Lisinopril

Answer 18

Angioedema, Hyperkalemia (as ANG2 stimulates Aldosterone). Cough (bradykinin)

Question 19

Angioedema, Hyperkalemia (as ANG2 stimulates Aldosterone). Cough (bradykinin) are side effects are:

Answer 19

Captopril, Enalapril, Lisinopril

Question 20

Contraindications of ACE inhibitors

Answer 20

Pregnancy

Question 21

Which ACE inhibitor is short acting and needs to be taken 3xs/day

Answer 21

Captopril

Question 22

Which ACE inhibitors are long acting and can be taken 1x/day

Answer 22

Enalapril, Lisinopril

Question 23

Spironolactone is what kind of drug

Answer 23

mineralcorticoid antagonist

Question 24

Which 2 drugs are mineralcorticoid drugs

Answer 24

Spironolactone and Eplerenone

Question 25

Which receptor does Eplerenone work on?

Answer 25

renal/aldosterone receptor

Question 26

Uses of Eplerenone

Answer 26

Diuretic, HTN, heart failure

Question 27

Uses of Spironolactone

Answer 27

Diuretic, HTN, heart failure

Question 28

Which receptor does Eplerenone work on?

Answer 28

aldosterone renal receptor

Question 29

What receptor does Spironolactone work on?

Answer 29

aldosterone renal receptor

Question 30

What are the uses of Eplerenone and Spironolactone?

Answer 30

diuretics, HTN and for heart failure

Question 31

B1, B2 adrenergic antagonist

Answer 31

Propranolol

Question 32

Receptor that propranolol acts on

Answer 32

B1 and B2

Question 33

Effects of Propranolol

Answer 33

Decrease HR, decrease renin release

Question 34

Uses of Propranolol

Answer 34

to treat hypertension

Question 35

Metoprolol is used to tx

Answer 35

hypertension

Question 36

Metoprolol acts on which receptor

Answer 36

B1

Question 37

Metoprolol works by:

Answer 37

Decrease HR, decrease renin release