Seronegatieve Arthritis Flashcards
what are types of seronegative arhtiris
reactive arthritis
ankylosing spondylitis
psoriatic arhtiris
what is sernogeaitve
it is the diagnosis without certain antibodies being present in the blood but with no symptoms
what is reactive arthritis
acute, non infection arthritis can follow a genitourinary or GI infection- salmonella or chylamida
infections of throat, GI
what does reactive arhtiris present as
joint inflammation around 2-4 weeks after large joint involvement fever and malaise conjunctivas urethritis arthritis conjunvcitivist iritis
what investigations should you do for for reactive arrhtiris
stool culture
genital swab
ct
how do you treat reactive arthritis
acute: NSADIS, joint injection, antibiotics
self limiting resolve in 3 monhts
what is ankylosing spondylitis
strongly associated with HLA b27
chronic inflammation in axial skeleton
increases in twins
leads to fibrosis and ossifaciiton
what are the clinical features of ankylosing spondylitis
low back pain that radiates to buttocks
tenderness over sacroiliac joints
chest expansion reduced
can lead to achilles tendonitis
what is ankylosing spondylitis associated with
antihero uveitis
pulmonary fibrosis
what investigations would you do
FBC-anemia
CRP
ESR
what is the criteria for axial sponfyloadhtiris
sacrolitis on imaging plys 1 feature-arhtiris, pain, psoriasis
HLSB27 plus 2 other features
what is the treatment of axial spondylitis
physiotherapy
NSAIDS
DMARD sulfasalazine
what is psoriatic arthritis
arthritis in people who have arthritis
where is it most common
neck.
shoulders
base of spine
wrists
what is the treatment for PA
sulfasalazine
methotrexate
steroids
anrti IL 17
