Sepsis Flashcards

1
Q

NICE traffic light system - red

crietira and action

A
systolic <90
HR >130
o2 <91
rr >25
AVPU = V, P or U
lactate >2
IMMEDIATE ACTION for any
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2
Q

ix

A
FBC
urine dip/MC+S
U+E -> dehydrationn/organ failure
LFT - hypoalbuminaemia likely
glucose - hyperglycaemia
clotting - DIC
2x blood cultures
scans
lactate
ABG
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3
Q

what may show on the ABG

A

metabolic acidosis

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4
Q

key immediate interventions

A
THE SEPSIS 6
1. high flow o2
2. blood cultures
3. IV abx
4. fluids
5. check Hb and serial lactates
6. hrly urine output measures
should be completed within 1 hr of intial identification
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5
Q

what level is highly predictive of death in sepsis

A

lactate.
<2 = 15% mortality
2-4 = 25%
>4 = 38%

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6
Q

definition of sepsis

A

life threatening organ dysfucntion caused by dysregulated host response to infection

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7
Q

signs of organ dysfuction

A

hypotension (SBP<90, MAP<65
hypoperfusion (serum lactate >2)
hypoxia <90% or needs O2
renal failure (<0.5ml/kg urine for 2 hr), creat >177
marrow and clotting (plts <100, INR >1.5, aPPT>60s

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8
Q

when are the sepsis 6 completed and within what time frame

A

any of the markers for sepsis present or SHEWS >3

perform within 1 hr

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9
Q

markers for sepsis

A
BP <90 systolic OR >40 drop of norm
HR >130
RR >25
O2 <90
URINE <30 ml/hr (NOT MEASURED PER KG)
lactate >2
cr >177
pt <100
appt >60 secs
INR >1.5
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10
Q

what are the sepsis 6

A
BUFALO
blood culture
urine output (hrly)
fluid challenges
abx (broad spec)
lactate
oxygen
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