semester 2 unit 1 Flashcards

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1
Q

Cell cycle

A

Interphase, mitosis, cytokinesis

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2
Q

Interphase stages

A

G1, S phase, G2

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3
Q

How many stages of mitosis? What are they?

A
  1. Prophase, metaphase, anaphase, telophase (cytokinesis follows mitosis).
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4
Q

How do you calculate mitotic index?

A

Mitotic index = number of cells in mitosis / total number of cells

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5
Q

What happens during G1 phase?

A

Gene expression and cellular respiration (producing ATP)

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6
Q

What happens during S phase?

A

DNA replicates creating two identical DNA strands

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7
Q

What happens during G2 phase?

A

Cell prepares to divide by replenishing energy, synthesizing proteins, and growing in size

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8
Q

What happens during prophase?

A

Chromosomes condense, forming two chromatids. Nuclear membrane disintegrates causing spindle to form.

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9
Q

What happens during metaphase?

A

Spindle organizes chromosomes on equator of the cell. Some spindle fibres attach to the centromeres and some span the cell. M-checkpoint occurs.

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10
Q

What happens during anaphase?

A

Some spindle shorten which pull the chromatids apart. Other spindle lengthen which cause cell to elongate.

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11
Q

What happens during telophase?

A

Two new nuclei form.

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12
Q

What happens during CYTOKINESIS?

A

The cell cytoplasm divides creating two new daughter cells.

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13
Q

What happens during INTERPHASE?

A

Cell spends most of their life in interphase. It grows and replicates its DNA/centrosomes in order to prepare for cell division.

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14
Q

What happens during MITOSIS?

A

The cell replicates and separates its chromosomes. The cell nucleus that holds the DNA divides into 2 equal parts.

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15
Q

How do plant cells divide?

A

Plant cells construct a new cell plate. The materials needed to do so are delivered by vesicles from Golgi.

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16
Q

How do animal cells divide?

A

A ring assembles in the middle of cell creating a cleavage furrow that moves inward (energy using process) to separate the two cells.

17
Q

When do plant cells begin cytokinesis?

A

Prophase

18
Q

When do animal cells begin cytokinesis?

A

Anaphase

19
Q

Cyclins

A

Cyclins control cell cycle progression by determining whether it will be fast or slow. Mutations in cyclin genes can lead to cancer. Cells cannot progress in cell cycle unless specific cyclins (D, E, A, B) reach a certain concentration.

20
Q

Cyclin D

A

Synthesized during G1. Triggers transition from G1 to S phase.

21
Q

Cyclin E

A

Synthesized during G1. Triggers transition from G1 to S phase.

22
Q

Cyclin A

A

Initiates DNA replication. Prepares centrioles for mitosis.

23
Q

Cyclin B

A

Progresses cell in & out of mitosis.

24
Q

What is mitotic spindle made of?

A

Microtubules and proteins

25
Q

Which cells have centrioles?

A

Animals have centrioles, plants have no centrioles.

26
Q

What’s chromatin?

A

Substance in cell’s nucleus that’s composed of primarily DNA and proteins

27
Q

What’s a chromatid?

A

One of the two identical halves of a chromosome that’s been replicated during cell division

28
Q

What’s a chromosome?

A

DNA molecule that holds genetic material

29
Q

Malignant tumor vs benign tumor

A

Malignant tumors grow rapidly and spread throughout the body destroying nearby tissues. Benign tumors grow slowly and don’t spread.

30
Q

Mutagen

A

An agent (radiation, chemical substance) that causes a genetic mutation

31
Q

Oncogene

A

A gene that can transform into a tumor cell

32
Q

Kinetochore

A

Protein complex that attaches to spindle & centromere