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Atilim Y2 Immunology > Self Study > Flashcards

Self Study Flashcards

1
Q

Leukocytes

A

White blood cells

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2
Q

Cells of innate immunity

A 
Macrophages monocytes mast cells 
Natural killer and neutrophils 
Basophils 
Dendritic cells 
Eosinophils
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3
Q

Neutrophils are …% of immune cells

A

60-70

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4
Q

First cell to respond to any infection

A

Neutrophils

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5
Q

Neutrophils are found in

A

Blood and they are very moblie

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6
Q

Neutrophil is a type of

A

Phagocyte

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7
Q

Nucleus of neutrophils

A

Multi lobed nucleus

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8
Q

…… granules per neutrophils

A

200-250

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9
Q

Poly morpho nuclear leukocytes

A

Nucleus has many morphologies like neutrophils

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10
Q

Enzymes produced by neutrophils

A

Myeloperoxidase
Defensins
Serine proteins

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11
Q

How is phagocytosis in neutrophils

A

The pathogen is trapped in the neutrophil in a phagosome which fuses with the lysosomes that has lysozyme which creates a phago lysosome which kills and digests that

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12
Q

What type of nucleus does eosinophils have

A

2 lobed nucleus

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13
Q

How much fo eosinophils make up of wbc

A

1-3%

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14
Q

What do eosinophils do

A

Fight multicellular parasites and bacteria

Responsible for many allergies like asthma

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15
Q

Least common wbc and how much is it?

A

Basophils

0.5-1%

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16
Q

Basophils function

A

Fighting parasitic infections and prevents blood clotting

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17
Q

How does basophil prevent blood clotting

A

It contains heparin

18
Q

Where are mast cells found

A

Connective tissues and mucous membrane

19
Q

Mast cells granules contains

A

Histamine and heparin

20
Q

Mast cells function

A

Wound healing
Microbal defense
Allergies
Link innate and adaptive

21
Q

What is histamine purpose

A

Dilate blood vessels

22
Q

What are macrophages

A

Large phagocytic cells that migrate from blood to tissue spaces for invading pathogens

23
Q

How do monocytes move

A

They circulate in the blood

24
Q

Neutrophils, eosinophils, and basophils are

A

Polu morpho neuclus cells

25
Q

What is chemokines purpose

A

Special chemical that attracts immune cells to the site of infection

26
Q

Dendritic cells are present in

A

Tissues in contact with external environment

27
Q

Dendritic cells are

A

Parts of antigen presenting cells

28
Q

Dendritic cells function

A

Present pathogens to lymphocytes (adaptive immunity)

29
Q

Dendritic cells are known as

A

Langerhans cells

30
Q

Natural killer cells function

A

Destroy the own body cells when they become defective

31
Q

Complement system definition

A

A set of 20 proteins used as a mechanism by the innate immunity system and it complements the actions of antibodies

32
Q

Antibodies purpose

A

When they find pathogens they attach to them

33
Q

Cells of acquired immune system

A

T lymphocytes
B Lymphocytes
( they are WBC)
And the antibodies produced by b and T cells

34
Q

The human body has …. lymphocytes which is ….%

A

2 trillion

20-40

35
Q

T lymphocytes are divided into

A

Helper T cells (CD4)

Killer T cells( CD8)

36
Q

CD 8 Function

A

Killing pathogens by directly interacting with microbes

37
Q

CD 4 cells function

A

Secret growth factors and cytokines

38
Q

Cellular immunity in adaptive immune system

A

T CELLS

39
Q

Humoral immunity in the adaptive immune system

A

B lymphocytes

40
Q

B lymphocytes purpose

A

Create antibodies for specific disease

41
Q

What is osponization

A

When antibodies bodies find a pathogen and attach to it coating it in antibodies which mark the pathogens so they can be destroyed by other cells

42
Q

Compare between innate and adaptive from response time

A

Innate immunity is more rapid

Atilim Y2 Immunology (10 decks)

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