Self Study Flashcards
Leukocytes
White blood cells
Cells of innate immunity
Macrophages monocytes mast cells Natural killer and neutrophils Basophils Dendritic cells Eosinophils
Neutrophils are …% of immune cells
60-70
First cell to respond to any infection
Neutrophils
Neutrophils are found in
Blood and they are very moblie
Neutrophil is a type of
Phagocyte
Nucleus of neutrophils
Multi lobed nucleus
…… granules per neutrophils
200-250
Poly morpho nuclear leukocytes
Nucleus has many morphologies like neutrophils
Enzymes produced by neutrophils
Myeloperoxidase
Defensins
Serine proteins
How is phagocytosis in neutrophils
The pathogen is trapped in the neutrophil in a phagosome which fuses with the lysosomes that has lysozyme which creates a phago lysosome which kills and digests that
What type of nucleus does eosinophils have
2 lobed nucleus
How much fo eosinophils make up of wbc
1-3%
What do eosinophils do
Fight multicellular parasites and bacteria
Responsible for many allergies like asthma
Least common wbc and how much is it?
Basophils
0.5-1%
Basophils function
Fighting parasitic infections and prevents blood clotting
How does basophil prevent blood clotting
It contains heparin
Where are mast cells found
Connective tissues and mucous membrane
Mast cells granules contains
Histamine and heparin
Mast cells function
Wound healing
Microbal defense
Allergies
Link innate and adaptive
What is histamine purpose
Dilate blood vessels
What are macrophages
Large phagocytic cells that migrate from blood to tissue spaces for invading pathogens
How do monocytes move
They circulate in the blood
Neutrophils, eosinophils, and basophils are
Polu morpho neuclus cells
What is chemokines purpose
Special chemical that attracts immune cells to the site of infection
Dendritic cells are present in
Tissues in contact with external environment
Dendritic cells are
Parts of antigen presenting cells
Dendritic cells function
Present pathogens to lymphocytes (adaptive immunity)
Dendritic cells are known as
Langerhans cells
Natural killer cells function
Destroy the own body cells when they become defective
Complement system definition
A set of 20 proteins used as a mechanism by the innate immunity system and it complements the actions of antibodies
Antibodies purpose
When they find pathogens they attach to them
Cells of acquired immune system
T lymphocytes
B Lymphocytes
( they are WBC)
And the antibodies produced by b and T cells
The human body has …. lymphocytes which is ….%
2 trillion
20-40
T lymphocytes are divided into
Helper T cells (CD4)
Killer T cells( CD8)
CD 8 Function
Killing pathogens by directly interacting with microbes
CD 4 cells function
Secret growth factors and cytokines
Cellular immunity in adaptive immune system
T CELLS
Humoral immunity in the adaptive immune system
B lymphocytes
B lymphocytes purpose
Create antibodies for specific disease
What is osponization
When antibodies bodies find a pathogen and attach to it coating it in antibodies which mark the pathogens so they can be destroyed by other cells
Compare between innate and adaptive from response time
Innate immunity is more rapid
