Micro Revision 2 Flashcards

1
Q

It is observed that a cytokine released from NK cells is a potent stimulator of macrophages. Which of the following substances is most likely elaborated by NK cells to stimulate macrophages?
• CD8 surface markers
• Interferon gamma
• N-formyl methionyl receptor • Nitric oxide synthetese
• Surface immunoglobulin

A

• Interferon gamma

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2
Q

As part of the innate immune response, which cells participate in phagocytosis?
• Macrophages and NK cells
• Macrophages and plasma cells, • NK cells and neutrophils
• Macrophages and neutrophils
• T cells and mast cells

A

Macrophages and neutrophils

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3
Q

Which of the following is not characteristic for innate lymphocyte cells?

  • They are lymphocyte-like cells
  • They produce cytokines
  • They express T cell antigen receptors
  • They provide early defense against infections • They are stimulated by cytokines
A

They express T cell antigen receptors

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4
Q

T cells interact with

A

other cells and not with soluble antigens,

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5
Q

T cell antigen receptors are designed to see

A

displayed by cell surface molecules

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6
Q

The specialized cells that capture and display antigens and activate T lymphocytes are called

A

antigen presenting cells (APCs

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7
Q

used to refer to specialized cells that display antigens to CD4+ T lymphocytes

A

APC

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8
Q

all nucleated cells can display protein antigens to

A

CD8+ T lymphocytes,

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9
Q

The displaying host cell–associated antigens for recognition by CD4+ and CD8+ T cells is performed by specialized proteins called

A

major histocompatibility complex (MHC) molecules

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10
Q

most effective APCs for activating naive T cells

A

Dendritic cells

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11
Q

Macrophages and B lymphocytes also function as APCs for

A

previously activated CD4+ helper T

Effector T cells

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12
Q

Dendritic cells, macrophages, and B lymphocytes express

A

class II MHC molecules

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13
Q

What happens after naive T cells are activated by dendritic cells

A

Differentiation into effector cells

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14
Q

What type of immunity occurs when macrophages initiate effector T cells by introducing a microbe

A

Cells mediated immunity

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15
Q

What type of immunity occurs when B cells initiate effector T cells by introducing a microbe

A

Humoral immunity

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16
Q

Dendritic cells that are resident in epithelia and tissues capture protein antigens and transport the antigens to

A

draining lymph nodes

17
Q

Resting tissue-resident dendritic express membrane receptors, such

A

C- type lectins, that bind microbes

18
Q

Dendritic cells use receptors to capture and endocytose microbes or microbial products and then process the ingested proteins into

A

peptides capable of binding to MHC molecules

19
Q

The dendritic cells are activated

A

cytokines, such as tumor necrosis factor (TNF), produced in response to the microbes
Microbal antigen binding