Final Flashcards
1
Q
Induces thrombocyr aggregation
A
TxA2
2
Q
Doesn’t have vasodilatory
A
Leukotriene c4
3
Q
Cause of increased vessel permeability in burns
A
Direct endothelial injury
4
Q
Not a chemotactic agent
A
Histamine
5
Q
Inflammation in diptheria
A
Pseudomembraneous
6
Q
Not an acute inf
A
Granulomatous inf
7
Q
L selectin fount in
A
WBC
8
Q
E selectin found in
A
Endothelial
9
Q
P selectin found in
A
Platelets
10
Q
Tnf induces
A
Inflammation
11
Q
Il 1 induces
A
Fever
12
Q
Chemokines il8, MIP
A
Attract neutrophils and macrophages
13
Q
Il6 induces
A
Acute phase proteins
14
Q
C5a
A
Attract neutrophils
15
Q
Cause of pain in inf
A
Low ph
16
Q
Splenectomy diseases bacteria example
A
S pneumonia
Neisseria meningitis
Hawkophilus influenzae
17
Q
Antibody meditated neutralization is done on exotoxins like
A
Corynebacterium, clostridium tetani
Clostridium botulinum
18
Q
Cause of redness in inf
A
Histamine
19
Q
Histamine is …. immunity
A
Innate
20
Q
MHC class 2 is what cells
A
Dendritic
B cell
Macrophages
21
Q
Nk cells participate in ADCC but they don’t
A
Initiate antigen presentation
22
Q
Bacteria mucosal surface immunoglobulin
A
IgA
23
Q
MHC function
A
Binds peptide antigen and presents to T cell
24
Q
This t cell helps isotype switching and antibody production
A
Tfh cell
25
IFN Gamma is not acossiated with
Plasma cell formation and antibody production
26
This cytokine inhibits the immune response
Il 10
| Ifn beta
27
Initial step in antibody is binding of antigen to b cell surface via
Bcr
28
Cytokine attracts neutrophils and inhibit bacteria
Il8
29
Antibody crosses placenta
IGg
30
This test detects num and type of immune cells in peripheral blood
Flow cytometry
31
PD 1 and CTLA 4 are targets for immune therapy and are bothe expressed on
Activated t cell
32
These cytokines attract neutrophils
Il8, il 17
33
Ige meduated histamine is what hypersensitivity reaction
Type 1
34
Which cell expresses receptors fro IgE on its cell and respond to worns
Mast cell
35
Laboratory assays considered to be invitro counterparts
IFN gamma treated with TB antigen
36
During second trimester of pregnancy
Liver
37
Where does affinity of hemoglobin increase
Hemoglobin f
38
Called as sinusoids, have large perforations, highly discontinous basement membrane
Discontinued cappillaries
39
Origin of heart tube
Splanchnic mesoderm
40
Doesn’t originate from the first phrngeal arch
Stapes
41
Disease associated with thymomas
Myasthenia gravis
42
Precursor lesion of squamous cell carcinoma
Squamous dystplasia
43
Patient who encounters tuberculosis bacillus for the first time
Supressed immunity
44
Which is non hodgkin lymphoma
Extranodal marginal zone
45
Nk produces ..... to stimulate macrophages
Inf gamma
46
Cd 4 releases a cytokine, its function is
Macrophages distraction of phagocytes microbes
47
Immunosuppressive cytokine
Il 10
48
This TLR. Recognizes lipopolysaccharite structure in outer membrane of gram negative bacteria (endotoxins)
TLR 4
49
Lassa fever
Occurs from contact of rodents
50
Anaphylatoxins
C3a, C4a
51
Secrets antibodies
Plasma cells
52
Causing agrnt of community acquired atypical pneumonia
Mycoplasma pneumonia
53
Transplant between different species
Xenografts
54
Pollen provikes which type of hypersensitivity
Type 1
55
Hypersensitivity thats t cell mediated
Type 4
56
Binds to mast cells, cause degranulation, release histamine
IgE
57
Type o blood lacks
Antigens
58
Type 2 hyper sensitivity cause
Mismatch blood type
59
Positive tuberculin tesr means
Delayed hypersensitivity
60
Tissue graft between not identical PEOPLE
Alloegraft
61
Examples of type 3 immune complex disease
Serum sickness
62
Graft when the recipient lacks immune system and the donor organ express different
hla
63
Agammmagloubinemia is deficiency in
B cells
64
Similar to aidS
SCID
65
Hiv high mutation because
Reverse transcriptase
66
Pregnancy test detects the presence if
Human chorionic gonadotropin
67
Autoimmune disease
Rheumatoid arthritis
68
Breastfeeding goves what type of immunity
Passive acqured
69
Molecules that increase ANC count (nutrophil)
Granulocyte CSF
70
A baby starts vaccination, his t cells are naive, t cells are dependent on which of the following molecular interactions
Binding of CD28 to B7-1 (CD80)
71
Pro inf cytokines
IL1, il6, TNF alpha
72
MALT
Dimeric ig with secretory components
73
Allergeb is
Molecule that bonds to antibody sensitizing the surface of mast cells
74
Primary immunodeficiency producing susceptibility to infections by viruses snd molds is caused by
T cell deficiency
75
Stess induced by excercise increases susceptibility to infection by
Raising plasma levels of cortisol
76
Produced by th2 CD cells wgich provide help for antobody production but not Th1 cells
IL4
77
Immunological memory can he transferred by
Lymphocytes
78
Statement about interferons
Induce enzyme synthesis in the target cells
79
Neutrophils defensibs are
Peptide antibiotics
80
Neutrophils contain
Microbicidial cytoplasmic granules
81
Which of the following doesn’t protect body surface
Salivary amilase
82
PRR includes which of the following
PAMPS
83
This cytokine promotes allergic response and inhibit cell mediated
IL 4
84
Signal transduction through TCR is enhanced by
CD 28
85
Oral vaccine
Mucosal IgA sectetion
86
What is activated by B7 expressed by B cells
CD 4 cell
87
What amels rheumatoid arthritis and endo toxic shock
TNF
88
After receiving flu shit by a month a man gets influenza, ehat cell prevents pneumonia
Memory lymphocyte
89
Not true about regulatory T cell
Control immune responses by lysing effector CD 4 T cells
90
IgE mediated histamine
Type 1
91
Naive T cells encounter antigen and start their activation where
Lymph node para cortex
92
Low ig G and memory b cells is impairment of
Th2 effector T cells
93
Il2 produced by
T cells
94
Il23 produced by
Macrophages and dendritic
95
Interaction of pathogen molecule with TLR directly results in
Cell activaton and production of cytokines and chemokines
96
Nk cells recognizes
MHC class 1 molecules
97
Antigen- antibidy conplexes are phagocytosed in the presence of
C3b
98
Primary lymphoid organ
Thymus
99
Statement about major histo compatibility is false
Surface proteins found in every cell
100
Lymph from lymph nodes with afferent lymphatic vessels enters first in
Subcapsullary sinus
101
Which structure is located between splinic sinusoids mainly composed of macrophages
Billroth cords
102
Prearteriolar lymphatic sheath in observed in
Spleen white pulp
103
This cell makes up hassal corpuscles
Epithelial reticular cells
104
The lymph fluid comes to lymph nodes passes which region first
Subcapsular sinus
105
Which lymphoid organ normally develops less functionality and high adipose with age
Thumus
106
The iron occurs most actively in
Spleen
107
Partly encapsulated and covered by non keratinized stratified squamous epithelium
Palatine tonsils
108
Thymic corpuscles (hassal) are composed of
Thpe VI reticular cells
109
In which organ medulla and hassal onserved in medulla
Thymus
