Segundos mensajeros y receptores

Question 1

Gi

Answer 1

Gi ->decreased cAMP activity through inhibition of adenylate cyclase-> α2

Question 2

α2

Answer 2

Gi ->decreased cAMP activity through inhibition of adenylate cyclase-

Question 3

increase intracellular calcium concentration through IP3 and DAG

Answer 3

Gq-> α1 -> smooth muscle contraction and vasoconstriction

Question 4

Gq

Answer 4

increase intracellular calcium concentration through IP3 and DAG-> α1

Question 5

increase intracellular calcium concentration through IP3 and DAG-> α1

Answer 5

Gq

Question 6

stimulated by β1 receptor binding

Answer 6

effect is an increase in cAMP

**not IP3 and DAG

Question 7

Gs

Answer 7

B1

Question 8

Glucagon binding causes activation of

Answer 8

adenylyl cyclase, leading to increase of cAMP in the cell and activation of protein kinase A

Question 9

receptor tyrosine kinase ligands

Answer 9

Insulin, insulin-like growth factor-1 (IGF-1), epidermal growth factor (EGF), platelet-derived growth factor (PDGF),
and fibroblast growth factor (FGF)

Question 10

Receptor tyrosine kinases regulate the

Answer 10

RAS/MAP kinase pathway

Question 11

Non-receptor tyrosine kinases regulate the

Answer 11

JAK/STAT pathway

Question 12

Immunomodulators (IL-2 and IL-6), prolactin, thrombopoietin, erythropoietin, growth hormone (GH), and
granulocyte colony stimulating factor (G-CSF

Answer 12

non-receptor tyrosine kinase ligands