Clinical Scenario//Inferred medication Flashcards
Patient is treated for a pulmonary embolism or deep vein thrombosis
Anticoagulation Heparin Warfarin Xa inhibitors -------------------
Patient is admitted for treatment of a congestive heart failure exacerbation
electrolyte changes :
Patient has a history of autoimmune disease (eg, systemic lupus erythematosus
Cushing syndrome, tertiary adrenal insufficiency, or avascular necrosis of the femoral head:
Patient has a history of rheumatoid arthritis
- Methotrexate-> pulmonary fibrosis,hepatotoxicity, oral ulcers
- hydroxychloroquine-> corneal deposits
- infliximab-> reactivated tuberculosis
Patient has a history of depression
Antidepressants
- SSRIs
- Serotonin-norepinephrine reuptake Inhibitor
- TCAs
- Monoamine oxidase inhibitors
Patient has a history of chronic headaches, joint pain, or back pain
Over-the-counter pain medications: Acetaminophen NSAIDs ---- chronic interstitial nephritis, renal papillary necrosis, decreased renal plasma flow, gastritis
Patient has a history of heart failure and atrial fibrillation
Digoxin
Patient was recently treated for a urinary tract infection y ahora tiene anemia hemolitica
G6PD deficiency
Patient was recently treated for tuberculosis
B6 deficiency (Pyridoxine) and sideroblastic anemia
Patient was treated for bacterial pneumonia or a chronic obstructive pulmonary disease exacerbation
QT prolongation and torsades de pointes
Patient was treated for herpes simplex virus encephalitis
crystalline nephropathy due to acyclovir therapy
Patient received chemotherapy for breast cancer
2
- *Tamoxifen -> increased risk of endometrial cancer
* *Trastuzumab-> dilated cardiomyopathy
Proxilaxis Neutropenic Fever
Temp > 38
Neutrofilos < 500
1) granulocyte colony-stimulating factor (GCSF) to stimulate granulocyte production
2) Antibioticos -> piperacillin-tazobactam, cefepime, vancomycin, and fluoroquinolones.
community-acquired pneumonia
Macrolidos (azithromycin and clarithromycin )
-binding to the 50S subunit of RNA
o
bind to the 30S subunit of RNA (Doxycycline)
————
Prolongan el QT
patients have been treated for pneumonia within the previous 3 months
Prolongan el QT y relacionadas a rotura del tendon de aquiles.
2)Penicillins act by interfering with the transpeptidation reaction in bacterial cell wall synthesis and inhibit peptidoglycan