Segars - Hormonal Contraceptives Flashcards

1
Q

Most common entity in HC

A

Ethinyl estradiol

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2
Q

Gonanes

A

Levonorgestrel, norgestrel, norgestimate, desogestrel, dienogest

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3
Q

Estranes

A

Ethynodiol diacetate, northindrone, norethindrone acetate

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4
Q

Receptor effects of gonanes

A

Progestinic & androgenic (except for dienogest)

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5
Q

Fixed dose of estrogen and progestin throughout cycle

A

Monophasic HC

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6
Q

Fixed dose of estrogen; lower progestin in first half of cycle with increased amount in second half

A

Biphasic HC

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7
Q

Increasing dose of estrogen (or progestin) 3x during the cycle

A

Triphasic HC

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8
Q

Decreasing dose of estrogen and increasing amounts of progestin 4x during cycle

A

Quadriphasic HC

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9
Q

Patch with EE, 7 day duraton

A

Norelgestromin

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10
Q

Vaginal ring with EE, 3 week duration

A

Etomogestrel

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11
Q

Available as progestin only implantable rod, 3 yr duration

A

Etonogestrel

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12
Q

Progestin only, long acting depo injection, 3 mo duration

A

Medroxyprogesterone

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13
Q

Progestin only IUD, available as 3 or 5 year device

A

Levonorgestrel

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14
Q

4 reducing non-contraceptive effects of estrogen

A

Cholesterol, AT-III, osteoclastic activity, bile acid levels

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15
Q

Pharm effects of HC

A

Modify LH & FSH surges

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16
Q

AE: srospirenone-containing agents

A

HyperK

17
Q

SAE: HCs

A

Systemic thromboembolism, HTN, gallbladder dz

18
Q

CI: HCs

A

Hx of vascular-related dz, pregnancy, neoplasm, un-dx’ed vaginal bleeding, uncontrolled HTN, smoker >/=35yo; d/t estrogen effects!

19
Q

EC can be administered up to

A

72 hrs after

20
Q

MOA: progestin (ECs)

A

Inhibition of ovulation

21
Q

Ella needs to be taken

A

Within 120 h

22
Q

MOA: ella (ulipristal)

A

Prgesterone-receptor modulator

23
Q

Only EC that needs prescription

A

Ella