Robbins Ch 22 - Lecture 4

Question 1

Use of IDU is ass’d with

Answer 1

2 fold inc of ectopic pregnancy

Question 2

MCC of hemtosalpinx

Answer 2

Tubal pregnancy

Question 3

Severe abdominal pain, vaginal bleering 6-8 weeks after LMP

Answer 3

Rupture of tubal preganacy

Question 4

Monochorionic placentas imply

Answer 4

Monozygotic twins

Question 5

Arteriovenous shunt directs blood flow to one twin at the expense of the other

Answer 5

Twin-twin transfusion syndrome

Question 6

Placents implants in the lower uterine segement or cervix, can lead to serious 3rd trimester bleeding

Answer 6

Placenta previa

Question 7

Predisposing factors to placenta accreta

Answer 7

Placent previa and previous c-section

Question 8

Partial or complete absence of the decidua, villous tissues adhere directly to the myometrium, failure of placental separation at birth, can cause life threatening postpartum bleeding

Answer 8

Placenta accretia

Question 9

MC type of ascending placental infection

Answer 9

Bacterial

Question 10

Cloudy, purulent amniotic fluid with inflitate of neutrophils and edema of placental vessels

Answer 10

Placental infection - ML bacterial

Question 11

MCC of ascending placental infections

Answer 11

TORCH group

Question 12

Widrepread maternal endothelias dysfuction that presents during pregnancy w/ HTN, edema, and proteinuria

Answer 12

Preeclampsia

Question 13

pregnant woman, HTN, proteinuria, edema, seizures

Answer 13

Eclapmsia

Question 14

HELLP syndrome

Answer 14

Hemolytic anemia, elevated liver enzymes, low platelets in the setting of severe preeclampsia

Question 15

Preeclampsia s/s disappear following

Answer 15

Delivery of the placenta

Question 16

2 placenta derives antiangiogenic factors that may be present/contribute to preeclampsia

Answer 16

SFtlt, endoglin

Question 17

Larger and more numerous placental infarcts, exaggerated ischemic changes in the choionic villi, increased syncytial knots, retroplacental hematomoas, abnormal decidual vessels

Answer 17

Preeclampsia findings in the placenta

Question 18

MC sites of thrombi in preeclampsia pts

Answer 18

Liver, kidneys, brain, (ant) pituitary

Question 19

Fertilized egg has lost F ch and genetic material is completely paternal

Answer 19

Complete mole

Question 20

Fertillization of an egg with 2 sperm

Answer 20

Partial mole

Question 21

Complete mole karyotype

Answer 21

46, XX or 46, XY

Question 22

Partial mole karyotypes

Answer 22

69 XXX, 69 XXY, 69 XYY (rare), can also be tetraploid - 92XXXY

Question 23

Delicate, fiable mass of think-walled, translucent, grapelike, cystic structures and edematous villi

Answer 23

Hydatidiform mole

Question 24

HCG levels are far elevation past normal for a pregnancy

Answer 24

Complete mole

Question 25

Complete moles can rarely give rise to

Answer 25

Gestational chiocarcinoma

Question 26

A mole that penetrate of perforated the uterine wall

Answer 26

Invasive mole

Question 27

Persistently elevated HCG, vaginal bleeding, irregular uterine enlargemnt

Answer 27

Invasive mole

Question 28

Malignant neoplasm of trophoblastic cells

Answer 28

Choriocarcinoma

Question 29

MC condition giving rise to choriocarcinomas

Answer 29

Complete hydatiform moles

Question 30

Soft, fleshy mass that is void of chorionic villi, and consists entirely of proliferating syncytiotrophoblasts and cytotrophoblasts

Answer 30

Chroriocarcinoma

Question 31

MC sites of choriocarcinoma mets

Answer 31

Lungs > vagina > brain > liver > bone > kidney

Question 32

Tx of choriocarcinoma

Answer 32

Chemo - good outcome!

Question 33

Neoplastic proliferations of extravilous trophoblasts

Answer 33

Placental Site Trophoblastic Tumor

Question 34

Polygonal monoculcear cells with abundant cytoplasm - produces human lactogen

Answer 34

PSTT

Question 35

Most impt predisposing condition to ectopic pregnancy

Answer 35

Pelvic inflammatory disease

Question 36

Spontaneous abortion is a pregnancy that is lost

Answer 36

Before 20 wk gestation