Seegars - MHT & SERMs

Question 1

How long doe menses need to cease to be called menopause?

Answer 1

12 mo

Question 2

Primary therapy for menopausal symptoms is

Answer 2

Estrogen

Question 3

A woman who is perimenopausal or menopausal WITH a uterus needs to be given

Answer 3

Progesterone - estrogen alone allows for hyperplasia an carcinoma risk

Question 4

6 forms of estrogen therapy

Answer 4

1) estradiol 2) CEE 3) synthetic conjugates estrogens A 4) synthetic conjugates estrogens B 5) EE 6) estropipate

Question 5

Best form of tx for women with vaginal symptoms only

Answer 5

Topical

Question 6

Ending of SERMs

Answer 6

-ifene

Question 7

Treats moderate-to-severe dyspareunia

Answer 7

Ospemifene

Question 8

Functions as estrogen agonist by binding to ER’s in vagina; anti-estrogenic on breast

Answer 8

Ospemifene

Question 9

Increased hot flases/ night sweat, vaginal discharge, estrogenic-effects on coagulation, endometrial hyperplasia

Answer 9

Ospemifene

Question 10

CI: ospemifene

Answer 10

Vaginal bleeding, thromboembolic dz, estrogen-related neoplasia

Question 11

Treatment of vasomotor sytmpoms ass’d with menopause and prevention of post-menopausal osteoporosis

Answer 11

Bazedoxifene (w/ CEE)

Question 12

Has all estrogen-related effects, PLUT hot flashes, abd and breast pain, leg cramps, HAs

Answer 12

Bazedoxifene (c/ CEE)

Question 13

CI: bazedoxifene

Answer 13

Same as CI’s for estrogen use!

Question 14

3 key time intervals for menopause

Answer 14

1) reproductive stage 2) menopausal transition 3) post-menopause