Section 15 Flashcards
most important factor contributing to patient mortality in TCA toxicity
Cyclic antidepressant–induced cardiotoxicity
most frequent dysrhythmia noted in cyclic antidepressant toxicity; bupropion; SNRI; MAOI
Sinus tachycardia
most common symptom reported after cyclic antidepressant exposure
Altered mental status
most potent sodium channel blocker among the cyclic antidepressants
desipramine
most frequently reported cardiovascular abnormality in trazodone
Orthostatic hypotension
most common ECG abnormality in trazodone
moderate prolongation of the QT interval
Most common form of pharmacotherapy for depression
SSRIs
associated with the highest incidence of seizures among the SSRIs.
Citalopram
most serious drug-related adverse effect of SSRI psychopharmacotherapy
Serotonin syndrome
drug class most commonly associated with serotonin syndrome.
antidepressant
most common cause of death in serotonin syndrome
severe hyperthermia
Most common cardiovascular manifestations of antipsychotic overdose
tachycardia and orthostatis hypotension
antipsychotics with highest rate of QT prolongation
amisulpride and thioridazine
antipsychotics with highest development of type 2 diabetes mellitus and diabetic ketoacidosis
olanzapine
most common disorder creating diagnostic confusion is serotonin syndrome
NMS
most prevalent endocrine dysfunction of chronic lithium therapy
hypothyroidism
most common class of antiepileptic drugs used in developing countries
Barbiturates
most common alcohols ingested
Ethanol and isopropanol