Science Section 3 Flashcards
When do you become aware of external stimulus
Only when the stimulus make its way up to the cerebral cortex that you become aware
What is phototransduction
when a receptor is activated by its preferred stimulus, the receptor is cell is depolarized leading to an action potential and or transmitter release
What cells transmit information out of the eye via action potentials potentials via their long axons
Retinal Ganglion Cells
Where is the blind spot in the eye
The point of where all these axons come together to exit out of the eye
What is the center of retina?
The center of the retina is called the fovea
What does the pupil do?
It the part of the eye that can dilate and contract to let light in
What functions do the pigmented epithelial cell have?
It has many functions as absorbing excess light, so it does not scatter and blur the images. and getting rid of the old, broken down segments of the photo receptors cells.
What are the two general photoreceptor cells
Rod & cones
How many cones are in cone systems are in a primate
There are three cones (Trichromantic) system
What do photoreceptor cells do when depolarized?
Release nuerotransmitter glutamate
why is the optic nerve considered a blind spot?
There are no photoreceptors there and no light can be transduced from this spot in the retina
Where do all the axons of the retinal ganglion cells come together?
The optic nerve
Amacrine cells can…
distribute information from one bipolar cell to many ganglion cells
Horizontal cells…
form connections between one central rod or cone to many other more distant photoreceptors and between several bipolar cells
Lateral Inhibition
refers to the capacity of excited neurons to reduce the activity of their neighbors, happens when a photoreceptor depolarizes a horizontal cell and the horizontal cell acts to inhibit the more distant bipolar cells
center-surround receptive fields
When neurons in the retina become stimulated, the neurons can choose to sharpen edges and enhance contrast in the images, creating clarity in the image
purpose of center-surround receptive fields
sharpen edges and enhance contrast in the images by amplifying the edges and borders
retinal edges in the fovea are very…
small, the horizontal cell connects fewer retinal ganglion cells to a single photoreceptor allowing highly acute vision
receptive fields in the peripheral parts f the retina are..
large and reduce less sharp vision
Once light has been transduced and processed the retinal ganglion cells…
transmit that information out the eye via action potentials down their long axons
retinofugal pathway
lating for feeling, the axons of the retinal ganglion exit at the back of the eye making up the optic nerve, and go all the ay back to the thalamus and then to the visual areas of the cerebral cortex
Optic chasim
the point where axons from both eyes come together as the cross targeting the thalamus on the opposite side of the head, named after the Greek letter “chi” which looks like an “X”
optic tract
the bundles of axons after reaching the optic chiasm, used to distinguish from the optic nerve
Left vs Right
Information about the left side of the world reaches the right side of the brain and vise versa
Binocular Vision
the central portion of the visual field seen by both eyes is represented by both sides of the brain, gives depth perception by the comparison of the difference in appearance seen by the right and left eye and calculating depth based off the different
lateral geniculate nucleus (LGN)
is a cluster of cell bodies in the thalamus (grey matter), specialized for processing visual input
LGN input layers
determine that the two eyes are not mixed; instead, the information is kept in distinct layers
Damage to the Ventral Extrastriate can cause…
Difficulty recognizing visual objects
What is Prosopagnosia?
Face blindness where the patient can’t recognize people by their face
What two parts make up the Inner Ear?
The Cochlea and Semicircular Canals
Where is the Primary Auditory Cortex located?
Within the Insular Cortex
What part of the brainstem calculates where a sound comes from?
The Nuclei of the Brainstem
Organ of Corti
where auditory transduction takes place
Hair Cells have an unusually low internal concentration of ______
Potassium
What is the auditory part of the thalamus called?
Medial Genniculate Nucleus (MGN)
A1
Primary Auditory Cortex
What is our oldest type of sense?
Chemical senses
What are the 5 types of taste?
sweet, sour, bitter, salty, and umami
What is the meaning of umami?
“deliciousness”
Who identified the taste of umami?
Japanese scientist Kikunae Idea in 1908
Umami is a major flavor of what food that is common in Japanese cooking?
Seaweed
The taste of umami is described as? And our sensory experience of chemical stimuli is based on what amino acid?
Its taste can be described as savory and is based on the amino acid L-glutamate
Sweet taste indicates the presence of?
Sugar and a food dense in calories
Sour foods indicate?
vitamins and minerals
Bitter tastes can warn us away from?
toxins
Salty foods are necessary for?
maintaining homeostasis
What are the bumps on your tongue called?
papillae
What is your organ of taste?
tastebuds
Where are tastebuds located in your tongue?
They can be found near/among the papillae and are in clusters of taste cells
What are tastebuds?
Barrel-shaped structures that consist of many sensory cells in clusters
What is a tastant?
a chemical particle in food that can be transduced by taste neurons
True or False? Each taste cell functions for multiple types of taste.
False. Each of the taste cell has one general type of taste receptor that is specific to one of the 5 basic tastes (i.e. the cell can be bitter or sweet but not both
True or False? Taste (gustatory) cell do not fire action potentials
True. They do not have to travel far until they reach the neuron which will then fire action potentials to send the signal to the brain. See Figure 53
Why do out taste cells become less responsive to continuous stimulus?
Because of sensory adaptation
dorsal column medial lemniscal (DCML) system
How touch and proprioception signals get sent from the tissues to the brain
Where is all somatosensation processed?
Primary Somatasensory Cortex
How does Pain and Temperature information get sent to the brain?
Anterolateral Spinothalamic System
M1
Primary Motor Cortex
Map or representation of the human body in the brain
Sensory Homunculus (From the latin Little Man)
What cells Synapse directly onto the muscles, causing involuntary movement?
Lower Motor Neurons
What is the most famous type of motor reflex?
Myotatic Reflex (Knee Jerk Response)
What functions are associated with the primary motor cortex (M1) and its related cortical areas?
Voluntary motion, planned sequences of action, and relaying commands to neurons to execute these functions
Where does the Corticospinal tract run from?
From Cerebral Cortex to the spine, beginning in the Primary Motor Cortex
Cerebellar deep nuclei
Provide output for the structure and the cerebellar cortex
is the circuitry system involved in learning
Yes, we learn through repetition in which our brain and body to ongoing motor command
What does the circulitry system do as organisms, interact with their environment
The sensory systems brings information of the world into the brain and motor system and the central nervous system brings behavioral commands out of the brain
how does the sensory system transduce environmental signals
It does this by the language of neurons, namely, action potentials and chemical neurotransmitters
Where does the visual system begin?
It begins in the photoreceptors of the retina, transducing light into an electrochemical signal
What does the cerebellum do?
It is the part of the brain not fully understood in the learning of the new motor task and skills
What does the Fastigial nucleus do ?
The Fastigial Nucleus receives input from sections of the cerebellar cortex and process vestibular, somatosensory auditory information, and visual information
What do indirect pathways do ?
Indirect pathways inhibit excess movement occurring that is not wanted.
Where does the Vestibulospinal tract originate?
It originates in the vestibular organs of the inner ear( such as semicircular canals) that provide information about the direction of gravity, spin and other forces on the body and head
Describe the transduction of salt tastants
1). Salt tastants enter the receptor cell through ion channels that are always open 2). This depolarizes the cell which causes voltage gated calcium channels to open 3). The opening causes an influx of calcium ions to enter the cell which then causes the release of serotonin filled vesicles
Describe the transduction of sour tastants
1). As the tastants are made of hydrogen ions, they enter the cell through open hydrogen channels 2). The influx of hydrogen and since the hydrogen ions inhibit potassium leak channels (which cause the membrane potential to become more neg. as a result of potassium leaving the cell) depolarizes the cell 3). Similarly salt, the depolarization causes the voltage gated calcium channels to open for in influx of calcium into the cell which in turn causes serotonin filled vesicles to be released into the synapse
How does the transduction of sour tastants differ from that of the salt tastants?
The hydrogen in the sour tastants inhibit potassium leak channels. This prevents potassium from leaving the cell and, therefore, helps depolarizes the receptor cell
The hydrogen in the sour tastants inhibit potassium leak channels. This prevents potassium from leaving the cell and, therefore, helps depolarizes the receptor cell
No, they bind to GPCRs (G-protein-coupled receptors, aka metabotropic receptors) and those are not ion channels
Describe the transduction of umami (like L-glutamate) and bitter tastants
1). The tastants activates GPCRs that are embedded in the membrane of the cell 2). Thus, activating the PLC pathway which causes the production IP3 (second messenger) from phospholipase C (PLC– effector protein 3). IP3 then goes to cause an influx of calcium into the cell by binding to receptors in the endoplasmic reticulum 4). This depolarizes the cell which causes the release of serotonin-filled vesicles but it also causes the voltage-gated calcium channels to open which will cause the release of serotonin-filled vesicles across the synapse
Describe the transduction of naturally occurring sweet tastants (such as saccharides)
The taste cell is depolarized by the activation of the GPCRs which causes PLC to be activated which in turn splits into IP3 and DAG. Then, DAG activates PKA (second messenger) which will then close nearby potassium channels (keeping the membrane potential more positive).
In what foods are saccharides (like sucrose) found?
Fruit and carbohydrates
Transduction of artificial sweeteners (like saccharine)
They activate different G-proteins which will then activate PLC to produce IP3 (similar to the umami and bitter pathways)