SCHIZOPHRENIA-biological therapies

Question 1

what type of biological therapies are there for schizophrenia?

Answer 1

drug therapy
ect
psychosurgery

Question 2

which biological therapy is most effective for schiz?

Answer 2

drug therapy

Question 3

what type of drugs is mainly used (bullet point 1)?

Answer 3

antipsychotic drugs mainly typical (affect dopamine) /atypical (affect serotonin levels)

Question 4

what about drug therapy point 2 /3?

Answer 4

2. dopamine plays an important role in schizophrenia development
3. antipsychotic drug therapy attempts to reduce the number of dopamine receptor sites by blocking them

Question 5

what are phenothiazines? (point 4)

Answer 5

function by blocking dopamine receptors e.g chlorpromazine

Question 6

what do these drugs do (point 5)?

Answer 6

these drugs reduce acute positive symptoms of schiz where max benefits are found within first 6 months

Question 7

what is point 6?

Answer 7

some drugs that block serotonin receptors are also used to treat schizophrenia e.g clozapine

Question 8

support for effectiveness of drug therapy cases?

Answer 8

julien

delima et al

Question 9

what happened in support in effectiveness for drug therapy in julien?

Answer 9

clozapine has been found as an effective treatment of schizophrenia

Question 10

opposition for julien?

Answer 10

antipsychotic drugs lack effectiveness in treating negative symptoms e.g loss of motivation

Question 11

another effectiveness for drug therapy?

Answer 11

antipsychotics produce a sedative effect and significantly reduce psychotic symptoms of hallucinations and delusions

Question 12

opposition for another effectiveness case?

Answer 12

rzewuska

Question 13

opposition for another effectiveness in rzewuska?

Answer 13

symptoms often return if the patient stops taking the drug

Question 14

what happened in support in effectiveness for drug therapy in delima et al?

Answer 14

serotonin moderating drugs can alleviate negative symptoms

Question 15

support/ opposition for effectiveness of drug therapy cases?

Answer 15

kemp et al
gualtieri
davis et al

Question 16

what happened in support in appropriateness for drug therapy?

Answer 16

more recently developed drugs more effective and cause fewer side effects

Question 17

opposition for appropriateness in drug therapy?

Answer 17

side effects:symptoms similar to those of parkinsons disease e.g stiffness,immobility and tremors. occurs in 30 % of patients using anti psychotics (gualtieri)

Question 18

what happened in support in appropriateness for drug therapy in kemp et l?

Answer 18

motivation interviewing techniques improve compliance to therapy

Question 19

opposition for kemp et al?

Answer 19

antipsychotics that affect serotonin levels result in damage to the immune system

Question 20

opposition in compliance for appropriateness of drug therapy?

Answer 20

davis et al- if antipsychotic drugs are stopped abruptly then symptoms recur. Patients often refuse to comply with treatment b.c side effects