Schizophrenia Flashcards

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1
Q

What’s a diagnosis?

A

deciding whether someone has a particular mental illness using classifications.

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2
Q

What’s schizophrenia?

A

it’s a type of psychosis characterised by a profound disruption of cognition and emotion so that contact with external reality and insight are impaired.

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3
Q

What is classification?

A

organising symptoms into categories based on which symptoms cluster together in sufferers.

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4
Q

What are positive symptoms?

A

symptoms that appear to reflect an excess or distortion of normal functioning

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5
Q

What are the positive symptoms of Schizophrenia?

A
  1. Hallucinations
  2. Delusions/Paranoia/Grandeur
  3. Disorganised speech
  4. Disorganised/catatonic behaviour
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6
Q

What are Hallucinations?

A

Distortions or exaggerations of perception in any of the senses, most notably auditory hallucinations.

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7
Q

What are Delusions?

A

Firmly held erroneous beliefs that are caused by distortions of reasonings or misinterpretations of perceptions or experiences.

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8
Q

What is Disorganised speech?

A

when an individual has problems organising his or her thoughts and this shows up in their speech.

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9
Q

What is disorganised/ catatonic behaviour.

A

includes the inability or motivation to initiate a task, or to complete it once it starts.

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10
Q

What are negative symptoms?

A

They appear to reflect a diminution or loss of normal functioning.

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11
Q

What is Speech Poverty?

A

The lessening of speech fluency and productivity, which is thought to reflect slowing or blocked thoughts.

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12
Q

What is Avolition?

A

A reduction of interests and desires as well as an inability to initiate and persist in goal-directed behaviour.

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13
Q

What is Affective Flattening?

A

A reduction in the range and intensity of emotional expression, including facial expression, voice tone, eye contact and body language

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14
Q

What are delusions of persecution?

A

the belief that others want to harm, threaten or manipulate you.

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15
Q

What are the delusions of grandeur?

A

the belief that they’re an important individual, even god-like have extraordinary powers.

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16
Q

What are delusions of control?

A

the belief that their body is under external control.

17
Q

What are the delusions of reference?

A

The belief that events in the environment appear to be directly related to them.

18
Q

What is a symptom overlap?

A

it’s the fact that symptoms of a disorder may not be unique to that disorder but may also be found in other disorders, making accurate diagnosis difficult.

19
Q

What is Co-morbidity?

A

the extent that two (or more) conditions or diseases occur simultaneously in a patient e.g schizophrenia and depression.

20
Q

What is Reliability?

A

How consistently clinicians come to the same conclusion using the (test-retest reliability) and agree with each other (inter-rater reliability)

21
Q

What is the dopamine hypothesis?

A

It claims that an excess of dopamine in certain regions of the brain is associated with positive symptoms of SZ

22
Q

What are neural correlates?

A

Changes in neuronal events and mechanisms that result in the characteristic symptoms of a behaviour or mental disorder

23
Q

What are cognitive explanations?

A

They’re explanations of mental disorders that propose that abnormalities in cognitive function are a key component of SZ.

24
Q

What are Dysfunctional thought processing?

A

Cognitive habits or beliefs that cause the individual to evaluate information inappropriately.

25
Q

What is Family Dysfunction?

A

The presence of problems within a family that contribute to relapse rates in recovering SZs, including lack of warmth between parents and child, dysfunctional communication patterns and parental overprotection

26
Q

What are Atypical antipsychotics?

A

they’re a type of antipsychotic that combat positive symptoms, have a beneficial effect on negative symptoms and cognitive impairment and carry a lower risk of extrapyramidal side effects

27
Q

What are typical antipsychotics?

A

they’re dopamine antagonists in that they bind to but don’t stimulate dopamine receptors and so reduce the symptoms of SZ

28
Q

What is family therapy?

A

It’s the name given to a range of interventions aimed at the family of someone with a mental disorder.

29
Q

What is token economy?

A

A form of therapy where desirable behaviours are encouraged by the use of selective reinforcements. Rewards (token) are given as secondary reinforcers when individuals engage in correct/socially desirable behaviours. the tokens can then be exchanged for primary reinforcers - food or privileges.

30
Q

What is the Diathesis - stress model?

A

It explains mental disorders as the result of interaction between biological (the diathesis) and environmental (stress) influences.

31
Q

what are the negative symptoms of schizophrenia?

A
  1. speech poverty
  2. avolition
  3. affective flattening
  4. anhedonia
32
Q

what is Anhedonia?

A

a loss of interest and pleasure in all or almost all activities, or a lack of reactivity to normally pleasurable stimuli.

33
Q

what are the genes implicated in schizophrenia?

A
  1. D2
  2. AMPA
  3. GRK
34
Q

What does the dopamine hypothesis state?

A
  1. Have too many D2 receptors.
    2.D2 receptors too sensitive/ fire too often
  2. they produce too much dopamine.
    (Only explains positive symptom
35
Q

What is family dysfunction?

A

The presence of problems within a family that contribute to relapse rates in recovering schizophrenics, including lack of warmth between parents and child, dysfunctional communication patterns and parental overproctection.

36
Q

What is dysfunctional thought processing?

A

Cognitive habits or beliefs that cause the individual to evaluate information inappropriately.

37
Q

Describe the key : Tienari et al. (2004)

A

procedure: Hospitals records were reviewed for nearly 20,000 women admitted to finnish psychiatric hospitals between 1960 and 1979, identifying those who had been diagnosed at least once with SZ or paranoid psychoses.
145 adopted away offspring (the high risk group) was then matched with a sample of 158 adoptees without this genetic risk ( low-risk group). Both groups were independently assessed after a median interval of 12 years, with a follow-up after 21 years

Findings: Of the 303 adoptees, 14 had developed schizophrenia. 11 were from the high risk group, 3 from low risk group

38
Q

Describe the key study of Pharoah et al, (2010)

A

Procedure: reviewed 53 studies published between 2002 and 2010 to investigate the effectiveness of family intervention. studies chosen were conducted in europe, asia and north america. The studies compared outcomes from family therapy to “standard” care (i.e antipsychotics medication) alone.
Findings:
Mental state: some studies reported an improvement in mental state of patients compared to those receiving standard care.
Compliance with medication: use of FT increase compliance with medication
Social functioning: showed some improvement but didn’t appear to have much of an effect on more concrete outcomes such as living independently or employment
Reduction in relapse and readmission: reduction in the risk of relapse and hospital admission during treatment and 24 months after