SAS 8 - ANS Flashcards

1
Q

Where do sympathetic originates from?

A

thoracolumbar

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2
Q

at what number of thoracic and lumbar?

A

thoracic 1-12
lumbar 1-5

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3
Q

where do parasympathetic originates from?

A

Craniosacral

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4
Q

at what number of cranial and sacral in parasympathetic?

A

cranial 3,7,9, 10; Sacral 3-4

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5
Q

What is the ganglion for acetylcholine?
*both S and PS

A

Nicotinic neural

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6
Q

Sympathetic
\/
postganglionic:
DA, Epi, and NE
\/
????

A

Alpha receptor, Beta receptor, and Dopamine receptor

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7
Q

An alpha receptor located in the post synaptic effector cells, especially smooth muscles

A

a1 receptors

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8
Q

Its general response is contraction

A

a1 receptor

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9
Q

An alpha receptor located in the vasomotor center

A

Presynaptic a2 receptors

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10
Q

what is the function of a2 receptor?

A

inhibition of norepinephrine release

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11
Q

an alpha receptor that is located in the peripheral blood vessels

A

postsynaptic a2 receptors

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12
Q

Its effect is vasoconstriction

A

Postsynaptic a2 receptor

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13
Q

A beta receptor that is located in the smooth muscles

A

B2 receptors

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14
Q

A beta receptor that is located in the adipose tissue

A

B3 receptor

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15
Q

A beta receptor that is located in the heart and juxtaglomerular apparatus

A

B1 receptor

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16
Q

where is the B1 receptor located?

A

Juxtaglomerular apparatus and heart

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17
Q

Where is the B2 receptor located?

A

Smooth muscles

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18
Q

Where is the B3 receptor located?

A

Adipose tissue

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19
Q

Its primary effect is contraction?

A

aplha 1 receptor

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20
Q

What is the other term of kidney?

A

Juxtaglomerular apparatus

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21
Q

what is increased inotropy means?

A

increase force of contraction

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22
Q

what is increase dromotropy means?

A

conduction velocity

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23
Q

what is increase chronotropy means?

A

increase heart rate

24
Q

What are the two cholinergic receptors in effector organs?

A

Muscarinic and Nicotinic receptors

25
Q

What are the different types of muscarinic receptors?

A

M1,M2,M3

26
Q

This muscarinic receptor is located in the eye, smooth muscle, exocrine glands

A

Muscarinic 3 receptors

27
Q

At what location is the Muscarinic 3 receptor found? -

A

eye, smooth muscle, exocrine glands

28
Q

This muscarinic receptor is found at nerve of gastric gland?

A

M1 receptor

29
Q

This muscarinic receptor is found at the heart?

A

M2 receptor

30
Q

A muscarinic receptor that causes bradycardia

A

M2 receptor

31
Q

What is bradycardia

A

Decrease in heart rate

32
Q

What is tachycardia

A

Increase in heart rate

33
Q

A muscarinic receptor that increased gastric acid secretion

A

M1 receptors

34
Q

A nicotinic receptor that is located in the ganglia and causes stimulation

A

Nn (Nicotinic Neural)

35
Q

A nicotinic receptor that is located in the neuromuscular end plate and causes skeletal muscle contraction

A

Nm (Nicotinic muscle contraction)

36
Q

What does NM do?

A

Stimulates contraction of skeletal muscle

37
Q

this receptor is found in the renal and splanchnic blood vessels

A

D1 receptor

38
Q

Where is D2 located?

A

Peripheral in GI and CNS

39
Q

What is the effect of B3?

A

Lipolysis

40
Q

Where is choline from and to where?

A

From the extracellular fluid and to neuron terminal

41
Q

prevent choline transporter to trasnports choline

A

HemCHOLINiums

42
Q

choline transporter is?

A

sodium dependent

43
Q

VAT is S or PS?

A

Parasympathetic

44
Q

VAT is driven by?

A

Proton efflux

45
Q

N-type calcium is it mentioned in S or PS?

A

Parasympathetic

46
Q

what prevents acetylcholine from releasing?

A

Botulinum toxin

47
Q

where do N-type calcium binds to?

A

VAMP synaptotagmin

48
Q

what process tyrosine undergoes to become DOPA?

A

Hydroxylation

49
Q

what enzyme is responsible for the HYDROXYLATION OF TYROSINE?

A

Tyrosinehydroxylase

50
Q

what drugs blocks tyroSINEhydroxylase?

A

MetyroSINE

51
Q

DOPA is decarboxlated to dopamine by what enzyme?

A

Aromatic L-amino acid decarboxylase

52
Q

VMAT is S or PS?

A

Sympathetic

53
Q

STORAGE:
VMAT (S) is blocked by?

A

Reserpine

54
Q

In calcium-dependent what drug blocks release of NE?

A

guanethidine

55
Q

In calcium-INdependent what persuades release of NE?

A

Cocaine, imipramine, duloxetine