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PHA 037 - PHARMACOLOGY > SAS 8 - ANS > Flashcards

SAS 8 - ANS Flashcards

1
Q

Where do sympathetic originates from?

A

thoracolumbar

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2
Q

at what number of thoracic and lumbar?

A

thoracic 1-12
lumbar 1-5

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3
Q

where do parasympathetic originates from?

A

Craniosacral

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4
Q

at what number of cranial and sacral in parasympathetic?

A

cranial 3,7,9, 10; Sacral 3-4

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5
Q

What is the ganglion for acetylcholine?
*both S and PS

A

Nicotinic neural

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6
Q

Sympathetic
\/
postganglionic:
DA, Epi, and NE
\/
????

A

Alpha receptor, Beta receptor, and Dopamine receptor

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7
Q

An alpha receptor located in the post synaptic effector cells, especially smooth muscles

A

a1 receptors

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8
Q

Its general response is contraction

A

a1 receptor

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9
Q

An alpha receptor located in the vasomotor center

A

Presynaptic a2 receptors

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10
Q

what is the function of a2 receptor?

A

inhibition of norepinephrine release

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11
Q

an alpha receptor that is located in the peripheral blood vessels

A

postsynaptic a2 receptors

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12
Q

Its effect is vasoconstriction

A

Postsynaptic a2 receptor

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13
Q

A beta receptor that is located in the smooth muscles

A

B2 receptors

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14
Q

A beta receptor that is located in the adipose tissue

A

B3 receptor

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15
Q

A beta receptor that is located in the heart and juxtaglomerular apparatus

A

B1 receptor

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16
Q

where is the B1 receptor located?

A

Juxtaglomerular apparatus and heart

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17
Q

Where is the B2 receptor located?

A

Smooth muscles

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18
Q

Where is the B3 receptor located?

A

Adipose tissue

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19
Q

Its primary effect is contraction?

A

aplha 1 receptor

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20
Q

What is the other term of kidney?

A

Juxtaglomerular apparatus

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21
Q

what is increased inotropy means?

A

increase force of contraction

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22
Q

what is increase dromotropy means?

A

conduction velocity

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23
Q

what is increase chronotropy means?

A

increase heart rate

24
Q

What are the two cholinergic receptors in effector organs?

A

Muscarinic and Nicotinic receptors

25
What are the different types of muscarinic receptors?
M1,M2,M3
26
This muscarinic receptor is located in the eye, smooth muscle, exocrine glands
Muscarinic 3 receptors
27
At what location is the Muscarinic 3 receptor found? -
eye, smooth muscle, exocrine glands
28
This muscarinic receptor is found at nerve of gastric gland?
M1 receptor
29
This muscarinic receptor is found at the heart?
M2 receptor
30
A muscarinic receptor that causes bradycardia
M2 receptor
31
What is bradycardia
Decrease in heart rate
32
What is tachycardia
Increase in heart rate
33
A muscarinic receptor that increased gastric acid secretion
M1 receptors
34
A nicotinic receptor that is located in the ganglia and causes stimulation
Nn (Nicotinic Neural)
35
A nicotinic receptor that is located in the neuromuscular end plate and causes skeletal muscle contraction
Nm (Nicotinic muscle contraction)
36
What does NM do?
Stimulates contraction of skeletal muscle
37
this receptor is found in the renal and splanchnic blood vessels
D1 receptor
38
Where is D2 located?
Peripheral in GI and CNS
39
What is the effect of B3?
Lipolysis
40
Where is choline from and to where?
From the extracellular fluid and to neuron terminal
41
prevent choline transporter to trasnports choline
HemCHOLINiums
42
choline transporter is?
sodium dependent
43
VAT is S or PS?
Parasympathetic
44
VAT is driven by?
Proton efflux
45
N-type calcium is it mentioned in S or PS?
Parasympathetic
46
what prevents acetylcholine from releasing?
Botulinum toxin
47
where do N-type calcium binds to?
VAMP synaptotagmin
48
what process tyrosine undergoes to become DOPA?
Hydroxylation
49
what enzyme is responsible for the HYDROXYLATION OF TYROSINE?
Tyrosinehydroxylase
50
what drugs blocks tyroSINEhydroxylase?
MetyroSINE
51
DOPA is decarboxlated to dopamine by what enzyme?
Aromatic L-amino acid decarboxylase
52
VMAT is S or PS?
Sympathetic
53
STORAGE: VMAT (S) is blocked by?
Reserpine
54
In calcium-dependent what drug blocks release of NE?
guanethidine
55
In calcium-INdependent what persuades release of NE?
Cocaine, imipramine, duloxetine

PHA 037 - PHARMACOLOGY (19 decks)

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