[sarcoidosis] Flashcards
HLA-DRB1
HLA-DQB1
erythema nodosum
polyarthralgia
erythema nodosum
polyarthralgia
inflammatory cells
inflammatory cells
inflammatory cells
CXR
BHL
bilateral hilar lymphadenopathy
BHL
bilateral hilar lymphadenopathy
bilateral hilar lymphadenopathy
lung fibrosis
pulmonary infiltrates
Dry
progressive
progressive cough
dyspnoea
chest pain
uveitis
Keratoconjuctivitis sicca
glaucoma
conjuctivitis
parotid
lacrimal
cardiomyopathy
arrhythmias
hepatomegaly
splenomegaly
SOL
meningitis
Bells palsy
hypercalciuria
inflammatory cells (non-caseating granulomas)
hypercalciuria
Ca2+ increased
increased
ACE
non-specific
ACE
non-specific
negative
+ think TB as well
negative
+ think TB as well
CXR
4
normal CXR
BHL (lymphadenopathy)
BHL
+
peripheral pulmonary infiltrates (parenchymal lung disease)
peripheral pulmonary infiltrates alone
pulmonary fibrosis
pulmonary fibrosis / honeycombing
diffuse pulmonary fibrosis (multiple bulla formation)
diffuse increased opacification with preservation of vascular and bronchial markings
diffuse increased opacification with preservation of vascular and bronchial markings
restrictive
tissue biopsy
restrictive
non-caseating granulomas
caseating = necrosis present (dead cells)
pulmonary fibrosis
active disease
active disease
terminal phalanges = punched out lesions
hypercalciuria
Ca2+ increased
terminal phalanges = punched out lesions
spontaneous resolvement
NSAIDs
Cardiac involvement Neurological involvement pulmonary infiltrates uveitis hypercalcaemia
prednisolone 40mg/24hrs PO for 4-6 weeks
prednisolone 40mg/24hrs PO for 4-6 weeks
Methylprednisolone IV
Methylprednisolone IV
6
infection malignancy sarcoidosis organic dust disease EAA Histocytosis X
TB
mycoplasma
lymphoma