[cystic fibrosis] Flashcards

1
Q
A

AR

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2
Q
A

caucasian

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3
Q
A

CFTR (CF transmembrane conductance regulator)

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4
Q
A

chloride (reduced reabsorption of Cl- from sweat into sweat duct, so increased Cl-. This ‘traps’ more Na in the sweat as well)

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5
Q
A

bronchiectasis

chronic infection

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6
Q
A

Sweat test

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7
Q
A

NaCl are >60 mmol/L

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8
Q
A

haemoptysis
wheeze
cough

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9
Q
A

pancreatic insufficiency (DM + steatorrhoea)

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10
Q
A

osteoporosis
sinusitis
vasculitis
hypertrophic pulmonary osteoarthropathy

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11
Q
A

clubbing of distal phalanges

periostitis (periosteum inflammation)

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12
Q
A

cirrhosis

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13
Q
A

obstructive

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14
Q
A

obstructive

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15
Q
A

Postural drainage
Abx or acute infective exacerbations
pancreatic enzyme replacement
ursodeoxycholic acid (liver replacement)

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16
Q
A

ADEK (fat soluble)

17
Q
A

bilateral coarse crackles

18
Q
A

faecal elastase

19
Q
A

chromosome 7

20
Q
A

bronchiectasis

pneumothorax

21
Q
A
thickened secretions
thickened secretions by liver to aid with digestion 
blocks ducts
cirrhosis 
clotting factors etc
22
Q
A
thickened secretions
thickened secretions by liver to aid with digestion 
blocks ducts
cirrhosis 
clotting factors affected
23
Q
A
thickened bile secretions 
block exocrine function
results in chronic damage to pancreas
painful pancreatitis
DM/steatorrhoea/ADEK
24
Q
A

Staph Aureus

Haemophilus influenzae

25
Q
A

pseudomonas aeruginosa