[fungus infection] Flashcards
Aspergillus
Candida
Cryptococcus
immunosuppressed
candida
cryptococcus
EAA - extrinsic allergic alveolitis
Asthma
Allergic bronchopulmonary aspergillosis
EAA to aspergillus clavatus
type 1 hypersensitivity
IgE - x-link with mast cells
immediate
IgM or IgG - antibody mediated
EAA - extrinsic allergic alveolitis Asthma Allergic bronchopulmonary aspergillosis invasive apergillosis aspergilloma
IgM or IgG - antibody mediated
f
a pre-existing cavity
TB
Sarcoidosis
cough
haemoptysis
lethargy
weight loss
CXR
round opacity within cavity
an antibody that precipitates out of the solution upon antigen binding
aspergillosis
Skin test
serum precipitans
sputum culture
Skin test
serum precipitans
sputum culture
infection
infarction
malignancy
aspergillus
infection
infarction
malignancy
Galactomannan
an aspergillus antigen
failure of body to mount an immune response
invasion of aspergillus into blood stream –> organs
failure of body to mount an immune response
invasion of aspergillus into blood stream –> organs
surgical excision
symptomatic
HIV broad spectrum Abx SLE Burns Leukaemia
HIV broad spectrum Abx SLE Burns Leukaemia
type 1
type 3
IgG - immune complex
cystic fibrosis
asthma
bronchoconstriction
immune complex deposition causing bronchiectasis
fungal hyphae
filamentous structure of a fungus (made up of multiple hypha cells)
filamentous structure of a fungus (made up of multiple hypha cells)
Allergic bronchopulmonary aspergillosis
bronchoconstriction –> fibrosis –> proximal bronchiectasis –> mucoid impaction and lobar collapse
bronchoconstriction –> fibrosis –> proximal bronchiectasis –> mucoid impaction and lobar collapse
bronchoconstriction –> fibrosis –> proximal bronchiectasis –> mucoid impaction and lobar collapse
recurrent pneumonia cough sputum dyspnoea wheeze
recurrent pneumonia cough sputum dyspnoea wheeze
CXR
consolidation
transient segmental collapse
bronchiectasis
normally air filled tissue filled with liquid/tissue
radioallergosorbent test
determine substances a patient is allergic to
via a blood test (cf. skin allergic test)
IgE
IgE
Bronchodilators
Prednisolone
Bronchodilators
Prednisolone 30-40mg/24hrs
eosinophilia
eosinophilia
test dose - 1mg in 20 mL to observe for anaphylaxis (SE)
test dose - 1mg in 20 mL to observe for anaphylaxis (SE)