Saponin glycosides Flashcards

1
Q

Form colloidal solutions in water that foam upon SHAKING (FROTH TEST)

A

Saponin glycosides

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2
Q

They have bitter, acrid taste and drugs containing them are usually sternutatory and otherwise irritating to the mucous membrane

A

Saponin glycosides

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3
Q

Destroy red blood cells by hemolysis and are toxic especially to cold- blooded animals

A

Saponin glycosides

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4
Q

The aglycones, usually prepared by acid- catalyzed hydrolysis, usually termed as

A

Sapogenins

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5
Q

form readily crystallizable compounds upon Acetylization

A

Sapogenins

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6
Q

Two chemical classes of saponin

A

Steroid, Triterpenoid saponins

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7
Q

the most important plant steroids for the partial

synthesis of steroid hormones

A

Diosgenin and botogenin

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8
Q

Steroid is from the genus

A

Dioscorea

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9
Q

Hecogenin, manogenin and gitogenin from species of

A

Agave

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10
Q

Sarsasapogenin and smilagenin from the genus

A

Smilax

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11
Q

have large number of carbon atoms ( C27 to C 30) making them lipophilic

A

Triterpenoid saponins

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12
Q

poisonous saponins

A

SAPOTOXINS

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13
Q

saponins have been used experimentally to enhance the absorption of __

A

insulin

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14
Q

From Greek origin means sweet root

A

GLYCYRRHIZA

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15
Q

GLYCYRRHIZA also called

A

LICORICE ROOT

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16
Q

means smooth, refers to the smooth , pod- like fruit of this species.

A

Glabra

17
Q

Just read

A

USES: gycyrrhiza

  1. Demulcent and expectorant properties
  2. Flavoring agent and mask the taste of bitter drugs such as aloe, ammonium chloride, quinine
  3. Surfactant
  4. Licorice is added to chewing gums, chocolate candy, cigarettes
  5. Added to beer to increase foaminess
  6. Imparts bitter taste when added to root beer, stout and porter
18
Q

saponinlike glycoside

• 50 times as sweet as sugar

A

Glycyrrhizin (Glycyrrhizic acid)

19
Q
  • pentacyclic triterpene derivative of the ß- amyrin type

- Use as anti- inflammatory agent

A

Glycyrrhetic acid

20
Q
  • Prepared by extracting coarsely ground licorice root with warm water, rendering the extractive alkaline with ammonium hydroxide, concentrating, and bringing it to final volume with alcohol and water.
  • It is a pharmaceutic aid
A

Glycyrrhiza fluidextract

21
Q

Prepared from glycyrrhiza and is a black pillular mass having a characteristic sweet taste

A

Licorice root extract

22
Q

Licorice root extract uses

A
  1. Used in the treatment of peptic ulcer and Addison’s disease
  2. Ingredient in aromatic cascara sagrada fluidextract
23
Q

is a popular name for several species of Discorea and is sometimes incorrectly applied to certain varieties of certain potato

A

Yam

24
Q

represents rich sources of principles used as cortisone precursors

A

Mexican yam

25
Q

are obtained from the root of Discorea spiculifora , a

cultivated species

A

Botogenin and diosgenin

26
Q

considered as the best source of steroids.

A

Mexican yam derived from D. floribunda

27
Q

the root of perennial herbs Panax quinquefolius Linne. (American Ginseng) and Panax ginseng (Fam. Araliaceae)

A

Ginseng

28
Q

Three categories of ginseng

A
  1. GINSENOSIDES
  2. PANAXOSIDES
  3. CHIKUSETSUSAPONINS
29
Q
  • one of the major saponins found in ginseng

* an example of a glycoside with a steroidal triterpene aglycone, ( 20S) –protopanaxatriol

A

Ginsenoside Rg1

30
Q

molluscicide

A

Agave

31
Q

Contains a complex mixture of triterpenoid saponins that can be either steroidal triterpenes or pentacyclic related tooleanoic acid

A

Ginseng

32
Q

Widely available in “ health- food” outlets

A

Ginseng