Polysaccharide and polysaccharide-containing drugs Flashcards
produced in large quantities in green leaves as the temporary storage form of photosynthetic product
Starch
an enzyme present in pancreatic juice and saliva, hydrolyzes starch by a random splitting of a 1,4- glucosidic linkages
a-amylase
produces its effect by removing maltose units from the non-reducing ends of polysaccharide molecules
B-amylase
end product in the case of amylase is
maltose
products of incomplete hydrolysis are polysaccharide fragments known as
dextrins
Mature grain of corn
Zea mays
Mature grain of wheat
Triticum aestivum
Tubers of the potato
Solanaceae
slightly soluble in cold water
used as tablet excipient
Pregelatinized starch
- A semisynthetic material, is the sodium salt of a carboxymethyl ether of starch
- It is used as a disintegrating agent in tablet formulations.
SODIUM STARCH GLYCOLATE
Is a semisynthetic material that is prepared in such a manner that is approx 90% amylopectin, and 7 or 8 hydroxyethyl substituents are present for each 10
glucose units
HETASTARCH
A 6% solution of hetastarch is used as a
plasma expander
it is obtained from the subterranean organs of members of the family Compositae
INULIN OR HYDROUS INULIN
Is an a-1,6-linked polyglucan that is formed from sucrose by the action of a transglucosylase enzyme system (dextran sucrase) present in Leuconostoc
mesenteroides
Dextran
Is a sterile, colloidal solution of ferric hydroxide in complex with partially hydrolyzed dextran of low molecular weight in water for injection
IRON DEXTRAN INJECTION