Salivary Gland Flashcards
1
Q
Most common gland affected in adults
A
Parotid gland
2
Q
Most common neoplasm in adults and children
A
Adults - pleomorphic adenoma
Children - mucoep ca
3
Q
Percentage of malignant transformation in PA
A
5- 10%
Another source: 3-15%
4
Q
Name the molecular abnormality in
1) PA
2) MASC
3) MEC
A
1) PA - PLAG1 (8q12)
2) MASC - ETV6-NTRK3
3) MEC - MECT1-MAML2 ( no prognostic significance)
5
Q
Percentage of lymph node involvement in adenoid cystic ca
A
5 to 25%, usually from submandibular gland
MYB gene translocation - diagnostic
