GI Flashcards
1
Q
Ganglioneuroma of the GI tract associated with what syndromes
A
MEN 2b
NF type 1
Cowden (PTEN mutation)
2
Q
Small cell carcinoma of the colon is associated with
A
Overlying adenoma, often villous/tubulovillous (30-40% of cases)
3
Q
Most common location for carcinoid tumors in GI tract
A
Jejunum and ileum
4
Q
Where do gastric hyperplastic polyps typically occurs?
A
Junction of pyloric and corpus mucosa.
Intestinal metaplasia may or may not be a component.
ONLY 2-3.5% undergo malignant transformation.
5
Q
Sessile serated adenoma harbor
A
> 1cm, right sided
MSI instability
BRAF mutation in 80%
6
Q
Patients with Barrett’s have a …… fold increased chance of adenocarcinoma ?
A
30 fold increases risk compared to gen population.
7
Q
HLA types associated with celiac disease
A
HLA-DQ2
HLA-DQ8
