Cytopath

Question 1

Follicular cervicitis associated with ….

Answer 1

Chlamydia infection

Question 2

When is HPV co testing done

Answer 2

Screening starts at 21 years of age for sexually active

21-29 : NO cotesting ( as HPV incidence)

30-64: screened at 3 year interval ( cytology exam only) OR 5 year intervals (cotesting)

Question 3

HSIL risk

Answer 3

Follow up biopsy of HSIL shows CIN2/3 in 75% of cases and

Invasive sq cell ca in 1.4%

Rx: colposcopy and biopsy and LEEP if suspicious

Question 4

Types of vaginal discharge with organism
Burning, itching and malodorous-
Thin, milky vaginal discharge with fishy odor -
Thick cheesy discharge -
Painful erosions and ulcerations -

Answer 4

Burning, itching and malodorous- T VAGINALIS
Thin, milky vaginal discharge with fishy odor - BACTERIAL VAGINOSIS (GV)
Thick cheesy discharge - CANDIDA
Painful erosions and ulcerations - HSV

Question 5

Adequacy criteria with minimal number of squamous cells in anal cytology on liquid based tests IS??

Answer 5

2000 to 3000

Question 6

Lung biomarkers

Answer 6

EGFR- mutations exon 18 to 21 in 10% western and 50% Asian patients

KRAS- seen more in adenoca associated with smoking (ADVERSE- predicts resistance to EGFR TKIs)

AlK REARRANGEMENTS seen in non-small cell lung ca.

Question 7

Small cell carcinoma cervix associated with HPV type ?

Answer 7

HPV18