Salamat D.O.C Flashcards

1
Q

Cyanide poisoning

A

Nitrite

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2
Q

Nitrite MOA

A

induces Methemoglobin formation

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3
Q

Nitrates in Angina

A
MOA:
-	Decrease in systemic vascular resistance
-	Vasodilates & Venodilates
S/E: headache
CI: Sildenafyl (Viagra)
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4
Q

Malignant Hyperthermia DOC:

A

Dantrolene

-Succinylcholine

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5
Q

Pheochromocytoma

DOC:

A
  • Phenoxybenzamine

- Phentolamine

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6
Q

Acute Gouty Arthritis DOC

A

Colchicine

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7
Q

Colchicine MOA

A

Inhibits Microtubule assembly

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8
Q

Chronic Gout DOC

A

Allopurinol

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9
Q

Allopurinol MOA

A

Inhibit Xanthine oxidase

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10
Q

Rheumatoid Arthritis + History of Peptic Ulcer

A

COX inhibitor

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11
Q

If (+) allergy to Penicillin give

A

Erythromycin

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12
Q

If (+) GI upset to Erythromycin

A

If (+) GI upset to Erythromycin

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13
Q

Still with allergy give

A

Linezolid

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14
Q

Choriocarcinoma DOC

A

Methotrexate

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15
Q

Methotrexate MOA

A

Inhibit Dihydrofolate reductase

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16
Q

Breast + Ovarian Ca DOC

A

Paclitaxel

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17
Q

Islet Cell Tumor DOC

A

Streptozocin

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18
Q

AML DOC

A

Cytarabin

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19
Q

Auer Rods

A

AML

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20
Q

Pancreatic Ca & Colon Ca DOC

A

5 FU

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21
Q

5 FU MOA

A

Inhibit thymidylate synthase

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22
Q

Bronchogenic Ca DOC

A

Cisplastin / Cyclophosphamide + Etoposide
-S/E: Hemorrhagic Ca
oTx: Mesna

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23
Q

Cisplatin Side effect

A

oOtotoxicity

oNephrotoxicity

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24
Q

Anti-neoplastic for Brain Tumors

A
  • Nitrosureas

- Lunostin, Corbostyl

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25
Q

iron Toxicity

A

Desferoxamine

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26
Q

Hemosiderosis

A
  • > 5 grams Iron/day

- Multiple drug transfusions

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27
Q

Organophosphate Poisoning

A
  • Atropine

- Pralidoxine

28
Q

Example of insectisides

A

Malathione/ Parathione

29
Q

Benzodiazepine Toxicity

A

Diazepam

DOC:Flumazenil

30
Q

INH Toxicity

A
  • Vit B6

- Pyridoxine

31
Q

Toxic Metabolite of INH

A

Acetylhydralazine

32
Q

Warfarin Toxicity

A
  • Vitamin K

- Fresh Frozen Plasma

33
Q

Heparin Toxicity

A

Protramine Sulfate

34
Q

Opioid / Narcotic Toxicity

A
  • Naloxone

- Ex. Morphine & Codeine

35
Q
  • Best cough suppression

- Mu Receptor

A

Codein

36
Q

Codein Side Effect

A

Respiratory Arrest

37
Q

Diabetic + Proteinuria

A

Angotensin Receptor Blocker/ ACE inhibitor

38
Q

Leptospirosis - Tx & Prophylaxis

A

Doxycycline

39
Q

Weil’s Disease Treatment

A

Penicillin

40
Q

Syphillis

A

Penicillin

41
Q

Bronchodilator to reduce uterine contractions in premature labor

A

Ritodrine

42
Q

Pre-op drug to control thyrotoxicosis

A

Propranolol

43
Q

Pre-op Bowel Prep antibiotic

A

Methylmycine/ Neomycine

44
Q

Decrease vascularity of thyroid gland pre-op

A

Lugol’s Solution

45
Q

Pheochromocytoma Pre-op

A

Phenoxybenzamine

46
Q

Induction anesthesia to decrease oral secretion

A

Atropine

47
Q

Most Cardiotoxic anesthesia

A

Bupivacaine

48
Q

Notorious to cause hepatitis

A

Halothane

49
Q

Laughing gas

A

Nitrous Oxide

50
Q

Diffuse Anoxia

A

Nitrous Oxide

51
Q

Status epilepticus

A
  • Barbiturates

- CI with phorphyria

52
Q

Causes dissociative Anesthetic

A

Ketamine

53
Q

Can penetrate Burn Eschar

A

Mefenide Acetate

54
Q

Drug for Asthma with Narrow Therapeutic Index

A

Aminophylline

55
Q

Synchonism

A

Quinine / Quinidine

56
Q

Anti-malarial drug for Relapse

A

Primaquine

57
Q

CYP 2 C9 Complex 1/ Electron Transport Chain

A

Phenobarbital

58
Q

Blocks Complex 1

A

Rotinone

59
Q

Blocks Complex 4

A

Cyanide & Carbon Monoxide

60
Q

Oligomycin

A
  • ATP Synthase
  • Fo fraction
  • Complex 5
61
Q

Blocks Complex 3

A

Blocks Complex 3

62
Q
  • Inhibit RENAL DIHYDROPEPTIDASE INHIBITOR
  • Prevents degradation of IMIPANEM
  • Imipanem + Cilastatin
A

Cilastin

63
Q

Carbidopa + Levodopa

A

-Carbidopa prevents the peripheral carboxylation of LEVODOPA (does not reach the brain)

64
Q

What is the DOC for Chronic Gout

A

-Allopurinol

o Inhibits xanthine oxidase

65
Q

Orlistat

A
  • Lipase inhibitor

- Causes flatulence & Steatorrhea