SAIDs (Glucocorticoids)

Question 1

Short acting Glucocorticoids

Answer 1

Perdnisone

Prednisolone

Methylprednisolone

Question 2

Intermediate acting Glucocorticoid

Answer 2

Triamcinolone

Question 3

Long acting Glucocorticoids

Answer 3

Dexamethasone

Betamethasone

Question 4

Moa of Glucocorticoids

Answer 4

You know it just say it

Question 5

Metabolic effects of Glucocorticoids

Answer 5

Hyperglycemia

Muscle wasting

Lipolysis

Osteoporosis

Question 6

Permissive effect of Glucocorticoids

Answer 6

facilitate the response of vascular

and bronchial smooth muscle to catecholamines.

Question 7

Anti-inflammatory and immunosuppressive effects of glucocorticoids

Answer 7

Reduced expression of COX and suppression of

phospholipase A2 →→ decreased production of prostanoids (PG, PC)

Question 8

Uses of Glucocorticoids

Answer 8

Replacement therapy (Addison’s disease).

Anti-inflammatory/immunosuppressive therapy

Septic shock

Topically in various inflammatory conditions of skin, eye, ear
or nose

Question 9

Toxicities of Glucocorticoids

Answer 9

Suppression of the response to infection or injury

Osteoporosis

Hyperglycemia

Muscle wasting

inhibition of growth

Hypertension

Edema

CNS effects: euphoria and psychosis