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PH2112 Metabolism: Phase 1 Oxidation > S-Oxidaton > Flashcards

S-Oxidaton Flashcards

1
Q

What happens in this reaction?

A

A Sulphur group with 2 lone pairs of electrons will be oxidised to have Two Oxygen groups linked with double bonds.

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2
Q

What enzymes are involved?

A

Flaroprotein oxidase and CYP enzymes

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3
Q

Give an example drug that undergoes this reaction

A

Omeprazole (but the product formed is NOT active)

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PH2112 Metabolism: Phase 1 Oxidation (12 decks)

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