Aliphatic Hydroxylation Flashcards
1
Q
State three facts about Aliphatic Hydroxylation
A
- Difficult to predict
- Quite variable
- Occurs in long and short chains
2
Q
What is Aliphatic Hydroxylation and what phase of metabolism?
A
Phase 1 metabolism adding an OH group to a C.
3
Q
What enzymes are involved?
A
CYP (Cytochrome P450 enzymes)
4
Q
What is more susceptible to Aliphatic HYdroxylation?
A
Electron rich Carbon groups are more susceptible to Aliphatic Hydroxylation
