Rubella Flashcards

1
Q

Rubella, previously called the german measles virus caused by the is a viral infection caused by the togavirus. What is the incidence of Rubella?

1 - 0.01 / 100,000
2 - 1 / 100,000
3 - 10 / 100,000
4 - 100 / 100,000

A

1 - 0.01 / 100,000

Incidence has reduced due to the Measles, Mumps and Rubella (MMR) vaccine

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2
Q

Rubella levels have significantly reduced thanks to the Measles, Mumps and Rubella (MMR) vaccine. Which 2 time points is the MMR vaccine given?

1 - 8-9 weeks
2 - 12-13 weeks
3 - 12-13 months
4 - 3 years and 4 months

A

3 - 12-13 months
4 - 3 years and 4 months

Given at 12-13 months and then a booster at 3 years and 4 months

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3
Q

Rubella levels have significantly reduced thanks to the Measles, Mumps and Rubella (MMR) vaccine. What age does the peak incidence of rubella occur?

1 - 1-12 months
2 - 1-2 years old
3 - 1-5 years old
4 - 5-10 years old

A

3 - 1-5 years old

Equally as common in boys and girls

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4
Q

If there is an outbreak of Rubella, when do these typically occur?

1 - Summer and Autumn
2 - Autumn and Winter
3 - Winter and Spring
4 - Spring and Summer

A

3 - Winter and Spring

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5
Q

What is the biggest risk factor for contracting Rubella?

1 - age
2 - gender
3 - unvaccinated
4 - maternal complications

A

3 - unvaccinated

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6
Q

How do patients typically contract Rubella cases?

1 - kissing infected person
2 - skin to skin contact
3 - touching infected surface (few hours)
4 - inhaling air droplets

A

4 - inhaling air droplets

Most common, but all others can also cause infection as well

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7
Q

Once a patient is infected with rubella, cells become infected and then new viruses bud off from infected cells. Which of the following can Rubella then infect?

1 - urine
2 - cerebrospinal fluid
3 - synovial joints and joints
4 - all of the above

A

4 - all of the above

Typically infects lymphatics and then moves through blood throughout the body

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8
Q

Can Rubella be transmitted from a pregnant mother to the foetus?

A
  • Yes

Most likely before 4 and 20 weeks, but after 20 weeks is less likely

Can cause congenital rubella syndrome and can lead to miscarriages, stillbirths, and a constellation of severe birth defects in infants can result.

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9
Q

Which of the following infections is NOT a common infection linked with causing congenital defects?

1 - Tuberculosis
2 - Toxoplasmosis
3 - Other infections (i.e. Syphilis)
4 - Rubella
5 - Cytomegalovirus
6 - Herpes Simplex

A

1 - Tuberculosis

Acronym TORCH can be used

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10
Q

Babies who contract Rubella whilst inside the womb can develop congenital rubella syndrome. This is typically associated with a triad, but which of the following is NOT one of these?

1 - trisomy such as down syndrome
2 - sensorineural hearing loss (deafness)
3 - eye abnormalities (cataracts and retinopathy, or damage to the retina)
4 - congenital heart disease such as Patent Ductus Arteriosus,

A

1 - trisomy such as down syndrome

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11
Q

Once infected with Rubella, what is the average incubation time?

1 - 7-10 days
2 - 10-14 days
3 - 14-21 days
4 - 21-35 days

A

3 - 14-21 days

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12
Q

Once infected with Rubella, the incubation time is typically 14-21 days. Which 2 are patients typically infected?

1 - 7 days from infection
2 - 7 days prior to symptom presentation
3 - once rash is present
4 - 4 days following rash onset

A

2 - 7 days prior to symptom presentation

4 - 4 days following rash onset

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13
Q

Do patients with rubella always show symptoms?

A
  • no

Patients can be asymptomatic, but symptoms begin after the 14/21 day incubation period

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14
Q

Which of the following is NOT a clinical symptom of Rubella?

1 - low grade fever
2 - conjunctivitis
3 - lymphadenopathy
4 - macular rash

A

2 - conjunctivitis

Low grade fever is typically a prodrome before the rash and lymphadenopathy occur

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15
Q

Rubella is associated with a maculopapular (macular = flat, and papules are raised areas of skin). Where does it typically begin?

1 - nappy area
2 - face
3 - legs and arms
4 - torso

A

2 - face

Then spreads to rest of the body

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16
Q

How long does the maculopapular (macular = flat, and papules are raised areas of skin) last for in Rubella infections?

1 - 24h
2 - 3-4 days
3 - 1 week
4 - 14-21 days

A

2 - 3-4 days

17
Q

Which 2 of the following locations does lymphadenopathy typically occur?

1 - suboccipital
2 - axillary
3 - inguinal
4 - postauricular

A

1 - suboccipital
4 - postauricular

18
Q

Do adults or children who contract Rubella show more symptoms?

A
  • adults

Typically sicker for longer

19
Q

Which of the following is NOT typically a complication of Rubella?

1 - arthritis
2 - thrombocytopaenia
3 - hepatitis
4 - encephalitis
5 - myocarditis

A

3 - hepatitis

20
Q

Which 2 of the following are used to diagnose Rubella?

1 - chest X-ray
2 - skin biopsy
3 - enzyme immunoassay
4 - PCR

A

3 - enzyme immunoassay
- detects antibodies

4 - PCR
- viral RNA is tested

21
Q

How is Rubella typically treated?

1 - antivirals
2 - oral antibiotics
3 - IV antibiotics
4 - supportive

A

4 - supportive