Mumps Flashcards
Mumps is caused by the mumps virus, which is a member of the paramyxoviridae family. What is the incidence of mumps?
1 - 2000 cases per 100,000
2 - 200 cases per 100,000
3 - 20 cases per 100,000
4 - 2 cases per 100,000
4 - 2 cases per 100,000
Mumps is caused by the mumps virus, which is a member of the paramyxoviridae family. What age does theincidence of mumps peak at?
1 - 1-12
2 - 10-25
3 - 30-40
4 - 50-60
3 - 30-40
Virus affects men and women equally
Is mumps a notifiable disease?
- yes
Need to notify the UK Health Security Agency ( UKHSA
Mumps is caused by the mumps virus, which is a member of the paramyxoviridae family. How do patients typically contract Mumps?
1 - kissing infected person
2 - skin to skin contact
3 - touching infected surface (few hours)
4 - inhaling air droplets
4 - inhaling air droplets
Most common, but all others can also cause infection as well
Typically, which part of the respiratory tract does the mumps virus infect 1st?
1 - nasopharynx
2 - oropharynx
3 - palatine tonsils
4 - epiglottis
1 - nasopharynx
Although mumps virus can affect multiple tissues, which tissues does it typically have the highest affinity for?
1 - palatine tonsils
2 - parotid glands
3 - eustachian tube
4 - sublingual glands
2 - parotid glands
Leads to swelling of the glands and can cause associated earache.
Can also cause trismus, spasm of muscles involved in chewing
Once inhaled, which 2 proteins are present on the cell surface of the mumps virus that facilitates binding and infecting host cells?
1 - p-peptides
2 - hemagglutinin-neuraminidase (HN protein)
3 - fusion (F protein)
4 - CD4
2 - hemagglutinin-neuraminidase (HN protein)
- helps bind to cells
3 - fusion (F protein)
- fuses membranes of virus and host cells
Once inhaled, mumps infected cells present their hemagglutinin-neuraminidase (HN protein) and fusion (F protein) on the cell surface of infected cells which leads to the formation of what?
1 - granulomas
2 - fibroblasts
3 - foamy macrophages
4 - multi-nucleated giant cell (syncytium)
4 - multi-nucleated giant cell (syncytium)
What is the incubation period for mumps?
1 - 4-5 days
2 - <11 days
3 - 14-21 days
4 - >21 days
3 - 14-21 days
Patients are infective 7 days before and 9 days after parotid swelling starts
In addition to an affinity for the parotid glands, the mumps virus has a lesser affinity for the CNS. Which 2 of the following are most likely to be caused by mumps if the CNS becomes infected?
1 - meningitis
2 - motor neuron disease
3 - multiple sclerosis
4 - encephalitis
1 - meningitis
4 - encephalitis
Symptoms can present like the common cold, headache, stiffness, hearing loss and balance problems.
Once infected with the mumps virus, which 2 of the following can occur in young boys and men?
1 - testicular torsion
2 - orchitis
3 - epididymitis
4 - ruptured appendix
2 - orchitis
- testicle inflammation
3 - epididymitis
- inflammation of the epididymis
Can cause testicular atrophy, but typically not infertility
Once infected with the mumps virus, what is the average incubation time?
1 - 7-10 days
2 - 10-14 days
3 - 14-21 days
4 - 21-35 days
3 - 14-21 days
Once infected with the mumps virus, which of the following determine when an individual is infective?
1 - immediately upon being infected
2 - 7 days from infection
3 - 4 days following rash onset
4 - 7 days prior to and 9 days following start of parotid swelling
4 - 7 days prior to and 9 days following start of parotid swelling
Which of the following is NOT a typical clinical presentation of mumps infection?
1 - fever and malaise
2 - conjunctivitis
3 - muscular pain
4 - parotitis (‘earache’, ‘pain on eating’): unilateral initially then becomes bilateral in 70%
2 - conjunctivitis
Which of the following can be performed to identify the specific pathogen for mumps?
1 - STI screen
2 - oral swab and PCR
3 - oral swab and ELISA
4 - culture
2 - oral swab and PCR
Findings would likely be:
- Mumps virus IgM: Detected
- Mumps virus IgG: Detected a low level