Rosh fam med eor boost exam Flashcards
____ ml of blood is heavy bleeding during menses
80
low estradiol and low progesterone causes ___ GnRH, FSH, LH
increased (all three)
A 25-year-old woman presents with a rash for the last 2 weeks. She reports it started with an approximately 2 cm oval salmon-colored patch on her anterior abdomen that began to clear about 1 week before more lesions appeared on her trunk. Lesions are pruritic. On physical exam, the patient has multiple oval-shaped salmon-colored patches with a collarette of scale over her trunk that follow the lines of cleavage in the skin. An image of her rash is shown above. Physical exam is otherwise unremarkable. dx?
pityriasis rosea
A 25-year-old woman presents with a rash for the last 2 weeks. She reports it started with an approximately 2 cm oval salmon-colored patch on her anterior abdomen that began to clear about 1 week before more lesions appeared on her trunk. Lesions are pruritic. On physical exam, the patient has multiple oval-shaped salmon-colored patches with a collarette of scale over her trunk that follow the lines of cleavage in the skin. An image of her rash is shown above. Physical exam is otherwise unremarkable.
Which of the following is the best therapy, given the suspected diagnosis?
topical corticosteroid
pityriasis rosea
-resolves in 2-3 mo
-hypothesis: viral in etiology
-tx: antihistamines, topical corticosteroids x3wks, severe = acyclovir, systemic glucocorticoids.
2 seizure types
focal and generalized
seizure type where there is no impairment of consciousness
simple partial seizure
seizure type where consciousness is impaired
complex partial seizure; with post ictal state
focal onset seizure
affect 1 cerebral hemisphere
seizure activity in both hemispheres and originate in midbrain or brainstem before spreading to cortices
generalized seizures
myoclonic seizures
<1 second, occur in mornings
take B6 with which TB med to prevent peripheral neuropathy
isoniazid
A 19-year-old man presents to his primary care provider with recurrent episodes of mild intermittent jaundice. He states these episodes began several years ago and seem to recur when he is stressed. He reports no other symptoms. Physical examination reveals mild scleral icterus and yellowing of the skin. Laboratory testing is significant for a slightly elevated indirect bilirubin. Which of the following best describes the pathophysiology of the most likely diagnosis?
Reduced production of uridine 5’-diphospho-glucuronosyltransferase
intermittent asx jaundice and scleral icterus
gilbert syndrome
-episodic jaundice triggered by stress, illness, physical exertion, hemolysis, fasting, menses, etoh use.
-no tx
-dx by labs showing high indirect bilirubin levels or genetic testing
pathophysiology of gilbert’s
inability to convert unconjugated bilirubin to conjugated bilirubin for excretion because of deficiency of youridine diphosphoglucuronosyltrasnferase
serum level of bilirubin associated with jaundice
> 3mg/dL
causes of unconjugated hyperbilirubinemia
hemolysis, gilbert syndrome, crigler najjar syndrome, drug reactions
causes of conjugated hyperbilirubinemia
dubin johnson syndrome, rotor syndrome, intrahepatic cholestasis, hepatitis, cirrhosis, sepsis, biliary obstruction
tension headache
bilateral in frontal occipital regions, vague tendernses of pericranial myofascial tenderness/trigger points
-stress and mental tension, fatigue, loud noise, glare, stress
-photophobia phonophobia
-not aggravated by routine physical activity
-triptans not effective
-amitriptyline is first line preventative tx
can also do cbt, stress management, relaxation, lifestyl
first line tx to prevent tension headaches
amitriptyline
-abortive tx for tension = nsaids
A 2-year-old boy who weighs 15 kg presents to the urgent care after his parents caught him eating acetaminophen 1 hour ago. They estimate he ingested between 6 and 10 tablets of acetaminophen 500 mg. The patient appears to be in no acute distress, and his vital signs are within normal limits. Which of the following clinical interventions is best to administer to this patient?
activated charcoal if dose is over 150 mg/kg and is within 4 hr of presentation
(not gastric lavage (risks>benefits), mag citrate (only adults), syrup of ipecac)
protocol for acetaminophen overdose
-if dose is over 150 mg/kg and is within 4 hr of presentation: activated charcoal unless AMS and intestinal obstruction
get serum acetaminophen level >4hrs after ingestion and then q1-2 hours after to plot elimination curve (Rumack Matthew Nomogram)
-administer N acetylcysteine if toxic levels
loss of central vision
age related macular degeneration
dry macular degeneration
atrophic
-more common
-gradual vision loss
-drusen deposits (protein deposits = yellow spots on retina)
wet macular degneration
wet macular degneration
supplements to slow down progression of macular degeneration
vit c, vit e, lutein, zeaxanthin, zinc, copper.
tx for wet age related macular degeneration
antivascular endothelial growth factors: bevacizumab and ranibizumab
-and/or photodynamic therapy
70-year-old man with a 50 pack-year history of cigarette smoking is being evaluated for possible community-acquired pneumonia. He has been coughing for 2 days but is currently afebrile. Physical exam is unremarkable. His chest radiograph reveals a single, well-circumscribed nodule, approximately 1 cm in diameter, at the periphery of the right lung. Which of the following is the best next step in management?
review a previous chest radiograph
(not CT, PET, or repeat chest imaging in 3 months)
-CT if no previous films for comparison or increased in size for >2 yrs, suggestive of ca, or no nodule on previous radiograph.
-PET for >1cm nodules
-if CT shows benign nodule then repeat chest imaging in 3 months
causes of lumbar radiculopathy
nerve root compression from spondylosis or disc herniation
most common site of disc herniations
L4-5, L5-S1
menopause
absence menses for 12 mo
-due to low estrogen and primary ovarian failure
-response: FSH increase
-mild sx: conservative measures like avoiding triggers, layers, lowering room temp
-persistent mod to severe sx: estrogen (in women with no uterus) or estrogen-progestin combo tx
constipation
MCC of acute bacterial sinusitis
strep pneumo
then Haemophilus influenzae
MCC chronic bacterial sinusitis
staph aureus
acute sinusitis
2 or more major criteria or 1 major and 2 minor criteria
major: facial pain/pressure/fullness, nasal obstruction, nasal discharge, purulence, hyposmia, fever
minor: headache, halitosis, fatigue, dental pain, cough, ear pain/pressure/fullness
highly suggestive of bacterial sinusitis:
sx>10days without improvement, acute onset of severe sx including 102 fever and purulent nasal discharge at onset, double sickening of fever, headache, rhinorrhea improving then suddenly worsening after 5-6 days.
tx for viral sinusitis
NSAIDS for pain, nasal saline sprays, mucolytics like guaifenesin, intranasal glucocorticoids, oral decongestants like sudafed, topical nasal vasoconstrictors like phenylephrine (<3days) or oxymetazoline.
first line tx for acute bacterial sinusitis
high dose amox or augmentin or doxy if penicillin allergy
painless hematochezia and iron deficiency anemia associated with what kind of colorectal carcinoma
right sided
-will see a decreased MCHC on CBC and decreased iron, ferritin, iron sat, increased TIBC and transferrin
changes in bowel habits and bowel obstruction associated with which type of colorectal carcinoma
left sided