Rodents Flashcards
What order are rodents in? What is the main characterisation of rodents?
Rodentia
Continuously growing incisors
What are the smallest and largest rodents?
Pygmy mouse
Capybara
What are the 2 main suborders of rodents (actually 5)?
Myomorpha = mouse like Hystricomorpha = porcupine like
What is the life expectancy of a mouse/rat/hamster/gerbil?
Mouse = 1-2.5 years Rat = 3 years Hamster/gerbil = 1.5-2 years
What is the life expectancy for a guinea pig/chinchilla?
Guinea pig = 4-7 years
Chinchilla = 10-15 years
What is the dental formula for a myomorph?
I 1/1
C 0/0
PM 0/0
M 3/3
What is the dental formula for a hystricomorph?
I 1/1
C 0/0
PM 1/1
M 3/3
Why is it possible to reduce the crown length using a dental burr, without anaesthetic? (Rodents)
Incisor pulp cavity is small and beneath the gumline
Never use nail clippers on teeth
Describe the root and growth of incisors, premolars and molars
All open rooted
All incisors continuously grow
Molars and premolars continuously grow in guinea pigs and chinchillas
What is the purpose of the large diastema in rodents?
Cheeks drawn in
Enables gnawing without wearing molars or swallowing
What is the lower to upper incisor crown ratio in myomorphs?
3:1
Normal to have much longer lower incisors
Rodent teeth are open rooted and incisors continuously grow, with most molars/premolars stopping growing. What are the terms for this?
Aradicular
Elodont - continuous growth
Anelodont - stop growing
What results in rodents having chisel shaped incisor teeth?
Hard enamel on rostral surface only
Softer dentine wears away quickly to form chisel shape
Why is dental disease common in guinea pigs and chinchillas?
Have elodont premolars/molars
Describe the stomach of rodents
Monogastric - simple stomach
Glandular stomach separated from fore stomach by ridge
Do rodents have a caecum? What shape is their colon?
Yes - large caecum
Elongated
What behaviour do rodents exhibit to enhance uptakes of essential minerals? Which minerals in particular is this for?
Coprophagy
Vitamin B and K
Are rodents able to vomit? Do they need starving before surgery? Why?
No
Don’t need starving as high metabolic rate and fast gut transit time
What type of breathers are rodents?
Obligate nasal
Mouth breathing = distress
How many lung lobes do rodents have?
Left - 1
Right - 4 (except hamster has additional)
For their size, rodents have high oxygen requiremens. How do they maximise their respiratory intake?
Short airways
Increased RR
Many alveoli of thin diameter
High chest wall compliance (increases vital capacity, decreases residual capacity)
Which way does the O2 haemoglobin saturation curve shift in smaller animals?
Right
Rodents are homeothermic endotherms. How do they manage thermogenesis in cold?
Behavioural - nest building
Shivering
Peripheral vasoconstriction
Non-shivering thermogenesis - brown fat for life
How do rodents manage to cool down when over heating?
Evaporation of saliva groomed over body
Arteriovenous shunts in ears, tails and feet
Sweat glands on feet
What type of uterus do rodents have? Which species is the exception?
Duplex - 2 cervices
Guinea pigs can be bicornuate OR duplex
How do litters vary between myomorphs and hystricomorphs (guinea pig is included in hystricomorphs)?
Myomorphs - altricial, short gestation, large litter
Hystricomorphs - smaller litters, long gestation, precocial young
How long is the oestrus cycle in mice/rats/hamsters, gerbils, guinea pigs and chinchillas?
Mice/rats/hamsters = 4-5 days
Gerbils = 4-7 days
Guinea pigs = 15-16 days
Chinchillas = 30-50 days
What type of ovulators are rodents? Which species is the exception?
Polyoestrus spontaenous
Chinchillas polyseasonal
Do rodents have a postpartum oestrus or not?
Yes
What age do myomorphs sexually mature?
6-8 weeks
What is the age of sexual maturity in guinea pigs and chinchillas?
Guinea pigs = 4-6 wks
Chinchillas = 8 months
What is the gestation period for mice, rats hamsters?
Mice = 20 days Rats = 22 days Hamsters = 17 days
Most rodents have many litters per year, with large numbers of offspring. What species is the exception?
Chinchillas
Have 2 litters per year
Only 2 offspring
What is the most reliable method to sex rodents? Why?
Anogenital distance - males longer
Stress inducing, absence of nipples/testes/penis in some species
Do all mice and rats have nipples?
Only females
Rodents have large testes. Can they be retracted?
Yes
Do all gerbils have nipples?
Yes but more prominent in females
Do all hamsters have nipples?
Yes - more obvious in females
Which species have nipples in both sexes?
Hamster, gerbils, guinea pigs
Which species only has nipples on females?
Rats, mice
What shape are the genitals in guinea pigs?
Female = Y Male = i
Do both sexes of guinea pigs have nipples?
Yes
Obvious inguinal
Why are chinchillas particulary difficult to sex?
External genital look similar - mistake penis for clitoris
Testes in inguinal canal
How can you determine the stage of oestrus in rats and mice?
Cytology of vaginal secretions
What is the method for cytology of vaginal secretions?
Flush vagina with distilled water
Air dry side
Stain
Count lymphocytes and epithelial cells - do they have nuclei
What are the 4 stages of the female repro cycle and how can they be distinguished?
Pro-oestrus - round, nucleated cells, few lymphocytes
Oestrus - few lymphocytes, few round nucleated cells
Metoestrus - mostly leucocytes (lots more than nucleated cells)
Diestrus - mostly leucocytes (more than nucleated cells)
What do female rodents often have after copulation? What is this? How long is it there?
Copulatory plug
Ejaculate which hardens within the cervix - seals vagina so mating more successful
8-12 hrs
High surface area to body ratio means that rodents are susceptible to what?
Hypothermia
Dehydration
Hypoglycaemia
Why are rodents obligate nasal breaths in terms of anatomy?
Larynx high up in oropharynx
Rats are nocturnal. Why are their incisors yellow? What is interesting about rat eyes?
Yellow incisors due to iron pigmentation (normal)
Prominent harderian gland - increased secretion when stressed/ill
What is unique about female rats and hamsters genitalia?
Urehral orifice separate from vulva in rats
Where can be used for venupuncture in rats? How much blood should be taken?
Lateral tail vein
Ventral tail artery
Lateral saphenous vein
Rats have extensive mammary glands. How many pairs do they have? What is a problem with this?
6 pairs
Prone to mammary tumours
How far do the cheek pouches extend in the hamster? What is often a problem with this?
Extend caudally to shoulder blades - store transport/flood, float in water
Often impaction
Site of immunological privilege
What is different about the stomach in hamsters?
Stomach separated like ruminants into forestomach and glandular stomach
Why are hamsters sensitive to antibiotics?
Disrupt normal gut flora
Which rodent has the shortest gestation?
Hamsters
Why is vaginal cytology hard to interpret in a hamster? Why is the vaginal plug difficult to see in hamsters? What can be seen instead?
Bilateral vagina pouches
Plug is deep
Vaginal discharge
What glands are found on the dorsal hamster? What hormones are they responsive to? Are they in both sexes?
Flank glands
Androgen responsive
Yes but more prominent in males
Do hamsters hibernate?
Yes if <5 degrees
Why is venipuncture difficult in a hamster? What sites should be used?
No tail vein
Jugular, cephalic or cranial vena cava
Like hamsters, gerbils have a deep vaginal plug. What is interesting about post-mating behaviour in gerbils?
Form monogamous pairs
Dad helps raise young
What large gland is found in gerbils of both sexes?
Ventral midline sebaceous gland
How do hamsters and gerbils differ in terms of water consumption?
Hamsters drink lots
Gerbils drink little
Why should gerbils not be handled by their tail?
Autonomy - can slough
What is unique about guinea pigs vitamin requirements?
Vitamin C essential
If not - scurvy within days
Male guinea pigs have prominent caudal sebaceous glands and large seminal vesicles. Why should females be bred before 7-8 months old?
Pubic symphysis dilates for parturition
If bred after - pubic symphysis fuses and dystocia
What can be used for venupuncture in a guinea pig?
Cranial vena cava
Jugular
Femoral or lateral saphenous vin
Where is the thymus in the guinea pig?
Cervical - surrounds trachea
Chinchillas are usually nocturnal but can be diurnal if needed. What ratio of light to dark period do they need?
12 hrs light
12 hrs dark
Chinchillas have very dense fur, 50-60 hairs from each follicle. What is significant about the coat?
Tolerant of cold
Sensitive to heat and wet
Drop coat if stressed
Require dust baths
Where can be used for chinchilla venupuncture?
Cranial vena cava
Lateral saphenous