Robbins Chapter 4 Key Concepts Flashcards
Protein-rich edema
exudative
Protein-poor edema
transudative
5 causes of edema
increased hydrostatic pressure decreased colloid pressure decreased lymphatic drainage increased vascular permeability (inflammation) sodium and water retention
How do thrombi develop
usually have one or more components of virchow triad
Virchow Triad
Endothelial injury
Abnormal Blood flow
Hypercoagulability
Endothelial Injury of Virchow Triad
associated with endothelial activation and changes in endothelial gene expression to favor coagulation
Abnormal Blood Flow of Virchow Triad
stasis or turbulence
Hypercoagulability of Virchow Triad
primary- factor V Leiden, increased prothrombin, antithrombin III deficiency
secondary- bed rest, tissue damage, malignancy, or development of antiphospholipid antibodies or antibodies against platelet factor IV/heparin complexes
Fates of thrombi
propagate
dissolve
embolize
organize
How can thrombi form tissue damage
local vascular occlusion or distal embolism