Chapter 6- Mixed Connective Tissue Disease and IgG4 Related Disease

Question 1

What is mixed connective tissue disease?

Answer 1

disease with mixed clinical features of SLE, systemic sclerosis, and polymyositis

Question 2

Later results of mixed connective tissue disease?

Answer 2

can evolve into classic SLE or systemic sclerosis

Question 3

Serious complications in mixed connective tissue disease (3)

Answer 3

pulmonary hypertension, interstitial lung disease, and renal disease

Question 4

Epidemiology of IgG4 Related Disease

Answer 4

middle-aged and older men

Question 5

Where is IgG related disease found?

Answer 5

all organs- salivary and lacrimal glands, thyroid, eyes, lungs, kidneys

Question 6

Characteristics of IgG4 Related Disease (4)

Answer 6

tissue infiltration by IgG4 antibody-producing plasma cells and lymphocytes
Storiform fibrosis
Obliterative phlebitis
Increased serum IgG4

Question 7

What is Obliterative phlebitis

Answer 7

Vein inflammation