Robbins chapitre 4 Flashcards
How long does it take for necrosis to show microscopically?
4-12 hours
Definition of shock
circulatory failure that impairs tissue perfusion and leads to hypoxia
GRAM + or GRAM - causes most often sepsis?
GRAM +
Which molecule blunts the vasomotor response in shock, causing vasodilatation instead of compensory vasoconstriction?
lactic acid
Which are the major types of shock:
cardiogenic hypovolemic, septic (and systemic inflammatory response syndrome, caused by burns, trauma, pancreatis, so non microbial insults)
Less frequent: neurogenic (spinal cord injury) and anaphylactic
Give 3 roles of thrombin in hemostasis and cellular activation (what they activate, what they deposit…)
- deposition of fibrin and platelet aggreggation on endothelial injury
- neutrophil adhesion
- monocyte activation
- lymphocytes activation
- endothelial activation
Name two proteins that activate platelets
Thrombin and ADP