Robbins chapitre 1 Flashcards
Which of those 2: phosphatidylinositol and phosphatidylserine gives a ‘‘eat mea’’ signal when flipped?
phosphatidylserine
2 ways plasma membrane proteins can be agreggated to form large complexes
chaperone molecules from the RER or lateral difusion
Anchoring junctions include: (3)
adherens junction, desmosomes/hemidesmosomes
Kinases phosphorylate tyrosine residue . Which protein removes those residues to modulate singaling?
phosphatase
what are major constituents of basal membrane?
type IV collagen (non fibrillar collagen) and laminin
name 1-3 adhesive glycoproteins
laminin
fibronectin
integrins
what is the job or CDK inhibitors?
enforcing the cell cycle checkpoints by modulating CDK-cyclin complex activity
Where are the 2 checkpoints in cellular cycle?
G1-S: check for DNA dammage
G2-M check for DNA dammage or unduplicated DNA.
symmetric va asymmetric division of stem cells
symmetric: both daughter cells can elf renew vs asymmetric: one of the 2 daughter cells cannot renew