Robbins 9th ed - Chapter 8 - Infectious Disease - Viruses (2)

Question 1

What is another name for the monospot test?

Answer 1

Heterophile antibody reaction.

Question 2

Which cell types are found in high numbers in patients with glandular fever?

Answer 2

There is a lymphocytosis, with large numbers of abnormal activated T-cells in the bloods (mononucleosis)

Question 3

EBV can cause neoplasms - which ones does it cause more commonly?

Answer 3

B-cell lymphomas, including Burkitt lymphoma.

Nasopharyngeal carcinomas.

Question 4

What type of virus is measles?

Answer 4

ssRNA virus of the paramyxovirus family.

Question 5

How is measles spread?

Answer 5

By respiratory droplets.

Question 6

What are the five classic clinical features of measles infection?

Answer 6

The three C’s: Cough, Coryza, Conjunctivitis

And: Fever, Rash.

Question 7

What is one clinical sign that is pathognomonic for measles?

Answer 7

Koplik spots: ulcerated mucosal lesions near the ducts of Stensen (salivary duct - parotid duct, in the mouth)

Question 8

What type of nucleic acid does adenovirus have?

Answer 8

dsDNA

Question 9

Which class of virus is polio?

Answer 9

Picornavirus (RNA)

Question 10

Which part of the nervous system does the polio virus infect?

Answer 10

The anterior motor units of the brainstem or spinal cord.

Question 11

What percentage of patients infected with the polio virus exhibit symptoms?

Answer 11

1%