Robbins 9th ed - Chapter 17 - Gastritis and PUD

Question 1

How does a stress ulcer develop?

Answer 1

As a consequence of shock, sepsis, or severe trauma.

Question 2

In acute gastritis, what is the rate of bleeding? What is the rate of ulcer perforation?

Answer 2

10-15% have bleeding

5% have perforation

Question 3

What is a feature that distinguishes between acute ulcers and ulcers as a result of chronic peptic ulcer disease?

Answer 3

Acute ulcers (e.g. stress ulcers) have normal mucosa adjacent to them. Chronic PUD has abnormal mucosa throughout the stomach.

Question 4

Name some causes of chronic gastritis.

Answer 4

From most common to least common:

• H.pylori infection
• Autoimmune gastritis
• Alcohol
• Tobacco
• Psychological stress
• Caffeine

Question 5

What proportion of the population are colonized with H.pylori?

Answer 5

10-80%. A much smaller percentage of these people actually develop gastritis.