Robbins 9th ed - Chapter 12 - Valvular Heart Disease (2)

Question 1

Which is the most common causal pathogen in infective endocarditis of damaged / abnormal heart valves?

Answer 1

Strep viridans

Question 2

Which is the most common causal pathogen in infective endocarditis of intravenous drug users?

Answer 2

Staph aureus

Question 3

Which is the most common causal pathogen in infective endocarditis of prosthetic heart valves?

Answer 3

Staph epidermidis (coagulase-negative Staph)

Question 4

What proportion of patients with strep pharyngitis will go on to develop acute rheumatic fever?

Answer 4

3%

Question 5

Approximately how long after a streptococcal infection does acute rheumatic fever manifest?

Answer 5

1-4 weeks (10 days to 6 weeks)

Question 6

According to the Jones criteria, acute rheumatic fever is diagnosed based on 1) a preceding group A strep infection, and 2) two major manifestations, or one major manifestation and two minor manifestations. Name the five major manifestations.

Answer 6

Migratory polyarthritis
Pancarditis
Subcutaneous nodules
Erythema marginatum 
Sydenham chorea

Question 7

In rheumatic heart disease, what is the name of the distinctive lesions of the heart, consisting of foci of T cells, macrophages, and plasma cells?

Answer 7

Aschoff bodies.

Question 8

In chronic rheumatic heart disease, what is the most common valvulopathy?

Answer 8

Mitral stenosis