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(1) VMCB > (RNA VIRUSES) Lesson 19: Paramyxoviridae > Flashcards

(RNA VIRUSES) Lesson 19: Paramyxoviridae Flashcards

1
Q

order Mononegavirales includes viruses within the ff families

A

Paramyxoviridae
Filoviridae
Bornaviridae
Rhabdoviridae

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2
Q

Families Paramyxoviridae, Filoviridae, Bornaviridae, and Rhabdoviridae are ancestrally related as reflected by their common characteristics such as:

ENUMERATE

A

✔ single- stranded genome of negative-sense RNA
✔ replication strategy and gene order
✔ virion morphology that includes an envelope

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3
Q

Genus under Filoviridae

A

Ebolavirus
Marburgvirus

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4
Q

OIE emerging dse under Family Filoviridae (Genus Ebolavirus)

A

Zaire ebolavirus

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5
Q

species under Family Filoviridae (Genus Marburgvirus)

A

Lake Victoria marburgvirus

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6
Q

Genera under Family Paramyxoviridae

A

Henipavirus
Avulavirus
Respirovirus
Rubulavirus
Morbillivirus

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7
Q

OIE listed dse under Family Paramyxoviridae

A

1) APMV-1 - Avian paramyxovirus type 1 (Newcastle disease virus)
2) Nipah virus
3) Peste-des-petits-ruminants virus
4) Rinderpest virus

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8
Q

OIE emerging dse under Family Paramyxoviridae (Genus Henipavirus)

A

Hendra virus

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9
Q

How many serotypes are there in Family Paramyxoviridae (Genus Avulavirus)

A

11 serotypes

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10
Q

Newcastle disease virus also known as

A

APMV-1 (Avian paramyxovirus type 1)

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11
Q

OIE listed dse under Family Paramyxoviridae (Genus Morbillivirus)

A

1) Peste-des-petits-ruminants virus
2) Rinderpest virus

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12
Q

Viruses in this family cause a number of serious respiratory and/or systemic diseases of humans, animals, and birds.

A

Paramyxoviridae

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13
Q

General description of Paramyxoviridae

A

✔ cause a number of serious respiratory and/or systemic
diseases of humans, animals, and bird
✔ virions are enveloped, pleomorphic (filamentous or spherical; approximately 150
nm or more in diameter)
✔ contain a genome of linear, negative-sense, single- stranded RNA
✔ viral nucleocapsid (ND virus) has helical symmetry (herringbone pattern) and is
approximately 13–18 nm in diameter
✔ Paramyxoviridae are monotypic

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14
Q

pattern of the helical symmetry of the Paramyxoviridae nucleocapsid

A

herringbone pattern

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15
Q

glycoproteins present at the surface or spikes of the Paramyxoviridae

A

✔ Fusion protein
✔ Hemagglutinin
✔ Neuraminidase

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16
Q

Antigenic property of Genus Avulavirus

A

✔
Fusion (F) protein
✔ Haemagglutinin (HA)
protein
✔ Neuraminadase (NA)
protein

17
Q

Antigenic property of Genus Morbillivirus

A

✔
Fusion (F) protein
✔ Haemagglutinin (HA)
protein

18
Q

Antigenic property of Genus Pneumovirus

A

✓ Fusion (F) protein

19
Q

network of rbc’s and viruses formed due to HA protein

A

Hemagglutination

20
Q

In hemagglutination, network of rbc’s and viruses formed due to what protein?

A

Haemagglutinin (HA) protein

21
Q

occurs when virus detaches from rbc’s due to neuraminadase (NA)
protein enzymes by breaking the contact of rbc and HA protein

A

Elution

22
Q

Elution occurs when virus detaches from rbc’s due to ____________ enzymes by breaking the contact of rbc and HA protein

A

neuraminadase (NA)
protein

23
Q

Paramyxoviridae are monotypic.

What does monotypic mean?

A

antibodies against one virus strain
can neutralize all strains of the same species

24
Q

is a highly contagious disease
of chickens that is characterized by respiratory distress, diarrhea, and
neurological signs (tremors, wing or leg paresis, torticollis, circling, spasms),
drop in egg production

A

Newcastle disease (ND)

25
Q

Newcastle Disease is caused by what virus?

A

Avian paramyxovirus type 1 (APMV-1) or
Newcastle disease virus

26
Q

First identified in Java, Indonesia (1926), and later in New Castle England
(1927)

A

Newcastle Disease

27
Q

Other names of Newcastle Disease

A

✓ Ranikhet Disease
✓ Pseudofowl Pest, Avian
✓ Pneumoencephalitis

28
Q

Severity of the Newcastle Disease is dependent upon the following

A

(1) age and immune status of
the birds
(2) the virulence of the strain of ND virus

29
Q

are
responsible for Avian paramyxovirus type 1 (APMV-1) or
Newcastle disease virus attachment to host cell and infection

A

✓ Fusion (F) proteins
✓ Hemagglutinin and Neuraminidase (HN)

(1) VMCB (15 decks)

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