(DNA VIRUSES) Lesson 10: Hepadnaviridae Flashcards
Hepadnaviridae literal definition
Hepa = liver; dna = deoxyribonucleic acid
It includes one virus that is pathogenic to man
Hepatitis B virus (HBV)
infecting liver cells, and all can cause hepatitis in their known host
hepatotropic
Are all of the known hepadnaviruses hepatotropic?
YES
syndrome characterized by inflammation of the liver
Hepatitis
It can be caused by hepatitis viruses (not necessarily in the Hepadnavirus family), other viruses, amoebas, and non-infectious agents such as alcohol and acetaminophen
Hepatitis
hepatitis viruses
amoebas
non-infectious agents: alcohol
and acetaminophen
these non-infectious agents causes hepatitis
alcohol and acetaminophen
these viruses are 60% genetically identical
Hepatitis B and Woodchuck Hepatitis Virus
These viruses differ from other DNA viruses by synthesizing their DNA by copying RNA using reverse transcriptase
hepadnaviruses
Why does hepadnaviruses differ from other DNA viruses?
Because it synthesized their DNA by copying RNA using reverse transcriptase
Hepatitis B (HBV) Diseases
ACS, hepatitis, cirrhosis, HCC
Ground Squirrel Hepatitis B Diseases
ACS, hepatitis, HCC
Woodchuck Hepatitis B Diseases
ACS, hepatitis, HCC
Duck Hepatitis B Diseases
ACS, hepatitis
Duck Hepatitis B Transmission
vertical
Heron Hepatitis B Transmission
vertical
Hepatitis B (HBV) Transmission
IDU, sexual, blood, vertical
Ground Squirrel Hepatitis B Transmission
Sexual, blood
Woodchuck Hepatitis B Transmission
Sexual, blood
Viruses under Genus Orthohepadnavirus
Hepatitis B (HBV)
Ground squirrel hepatitis B
Woodchuck hepatitis B
Viruses under Genus Avihepadnavirus
Duck Hepatitis B
Heron Hepatitis B