(DNA VIRUSES) Lesson 6: Parvoviridae

Question 1

General description of Parvoviridae

Answer 1

 Small, non-enveloped, single-stranded DNA viruses
 Icosahedral symmetry
 Replicate in the nucleus, form intranuclear inclusion bodies
 Require rapidly dividing cells for replication
 Stable in the environment
 Resistant to heat, solvents, disinfectants, and pH changes

Question 2

Parvoviridae replicate in the nucleus and form what?

Answer 2

intranuclear inclusion bodies

Question 3

Parvoviridae replicate here

Answer 3

nucleus

Question 4

Genus Parvovirus general characteristics

Answer 4

 Manyhavehaemagglutinating activity
 Shedinlarge numbers in faeces
 Enteric and systemic diseases in dogs and cats
 Reproductive failure, SMEDI syndrome in pigs

Question 5

Genus Parvovirus is shed through what?

Answer 5

feces

Question 6

it causes reproductive failure, SMEDI syndrome in pigs

Answer 6

Genus Parvovirus

Question 7

In the family Parvovridae, members of this genus are of veterinary importance

Answer 7

Parvovirus

Question 8

Causative agents of erythema infectiosum in children

Answer 8

Human Parvovirus B19

Question 9

Human Parvovirus B19 causes what?

Answer 9

Erythema Infectiosum in Children

Question 10

Human Parvovirus B19 is under in this genus which causes Erythema Infectiosum in Children

Answer 10

Erythrovirus

Question 11

viral disease under Genus Amdovirus

Answer 11

Aleutian mink disease virus

Question 12

viral diseases under Genus Bocavirus

Answer 12

Bovine parvovirus
Canine minute virus

Question 13

viral disease under Genus Erythrovirus

Answer 13

Human Parvovirus B19

Question 14

this genus is usually dependent on adenoviruses for replication

Answer 14

Dependovirus

Question 15

Members of this subfamily infect arthropod

Answer 15

Densovirinae

Question 16

one of the most common feline viral infections

Answer 16

Feline panleukopenia virus / feline infectious enteritis / feline distemper

Question 17

What stage does virus shedding of Feline panleukopenia virus occur?

Answer 17

acute stage

Question 18

Virus shedding occurs during acute stage mainly in __________ but also
in ____________________.

Answer 18

faeces
saliva, urine, vomitus and blood

Question 19

Virus shedding of the Feline panleukopenia virus in feces may persist even after clinical recovery.

TRUE OR FALSE

Answer 19

TRUE

Question 20

Subclinical carriers of the Feline panleukopenia virus transmit the virus thru what?

Answer 20

low-grade shedding

Question 21

Feline panleukopenia virus is stable in these environment

Answer 21

cool, moist, dark areas

Question 22

It may act as a mechanical vectors of Feline panleukopenia virus

Answer 22

Fleas and humans

Question 23

Feline panleukopenia virus is diagnosed through what?

Answer 23

Serology (ELISA, canine parvovius kit may be used, VNT)
PCR

Question 24

Feline panleukopenia virus is controlled through what?

Answer 24

vaccines
disinfection in contaminated area

Question 25

disease in dogs with high morbidity and mortality

Answer 25

Canine parvovirus (CPV)

Question 26

Three subtypes of Canine parvovirus (CPV)

Answer 26

CPV-2a
CPV- 2b
CPV-2c

Question 27

clinical presentation is common in (acute enteric disease) in young dogs between ________ and _______.

Answer 27

weaning and 6 months of age

Question 28

This viral disease is rare in cats

Answer 28

Canine parvovirus (CPV)

Question 29

Transmission of

Answer 29

oro-fecal route
mechanical transfer (vectors)

Question 30

Canine parvovirus (CPV) is diagnosed through what?

Answer 30

Fecalysis
Collecting blood and affected tissues (intestines and myocardium)
Leukopenia or basophilic inclusion bodies in cardiac myocytes
Commercial test kit

Question 31

specimen to be collected to diagnose

Answer 31

feces
blood
affected tissues (intestines and myocardium)
leukopenia, or basophilic inclusion bodies in cardiac myocytes

Question 32

Canine parvovirus (CPV) is controlled through what?

Answer 32

vaccines
disinfection in contaminated area

Question 33

an important cause of reproductive failure in pigs

Answer 33

Porcine parvovirus

Question 34

Porcine parvovirus are shed thru what?

Answer 34

feces
other secretions including semen

Question 35

Highly contagious systemic and enteric disease most common in weaned kittens, manifested by depression, vomiting, diarrhoea. Intrauterine infection: abortion or cerebellar ataxia in neonatal kittens

Answer 35

Feline panleukopenia virus

Question 36

Highly contagious enteric disease with depression, vomiting, dysentery and immunosuppression. Intrauterine or perinatal infection: myocarditis in pups (rare)

Answer 36

Canine parvovirus (canine parvovirus 2)

Question 37

Major cause of stillbirths, mummified foetuses, embryonic deaths and infertility (SMEDI syndrome)

Answer 37

Porcine parvovirus

Question 38

Generalized disease of mink kits, analogous to feline panleukopenia

Answer 38

Mink enteritis virus

Question 39

Chronic progressive disease of mink homozygous for pale coat colour. Persistent viraemia, plasmacytosis, hypergammaglobulinaemia and immune complex-related lesions

Answer 39

Aleutian mink disease virus

Question 40

Highly contagious, fatal disease of 8 to 30-day-old goslings (Derzsy’s disease): hepatitis, myositis, including myocarditis

Answer 40

Goose parvovirus (goose plague virus)

Question 41

High mortality, clinical signs and lesions similar to goose parvovirus

Answer 41

Duck parvovirus

Question 42

Role of virus in disease is uncertain; serological surveys suggest the virus is widespread

Answer 42

Canine minute virus (canine parvovirus 1)

Question 43

Associated with sporadic outbreaks of diarrhoea in calves

Answer 43

Bovine parvovirus