Ribosomes + ER Flashcards
Which of the statements about ribosomes in false?
They contain DNA and protein!
What happens to DNA, mRNA then protein?
DNA is replicated, transcribed into mRNA, then mRNA is translated into protein!
Where are the majority of rRNAs synthesised?
Which rRNA is the exception?
Nucleolus!
5S - still made in nucleus though!
The nucleolus is where…
Ribosomal rRNA is made
The GENES coding for the majority of rRNA are found…
Clustered on SPECIFIC chromosomes
The nucleolar organisers are…
Chromosomal regions around which the nucleolus forms!
Which processes contribute to the production of MATURE 28S rRNA?
RNA Cleavage
Transcription
Chemical Modification
Where are ribosomal subunit ASSEMBLED?
Nucleolus!
Where are ribosomal PROTEINS TRANSLATED?
Cytoplasm!
Where are BOTH subunits assembled (complete!)?
Cytoplasm - ONLY when encounter mRNA
Where are ribosomal PROTEINS transcribed?
Nucleus
Majority of rRNAs are produced in… from multiple… found on… chromosomes. Regions containing these clusters are known as…
Nucleolus
Genes
10
Nucleolar organisers!
The three MATURE RNAs are:
28S
18S
5.8S
Which subunit contains the mRNA binding groove?
Small!
Which part of ribosome does incoming AA acyl-tRNA first interact?
The A- site
In what direction is mRNA read during translation?
5 to 3
In what direction are proteins synthesised?
N TO C
What is catalytic RNA called?
Eg?
Ribozyme
28S rRNA
The start codon is… and encodes for the AA…
AUG
Methionine
How many stop codons does the STANDARD Eukaryotic genetic code contain?
3 - UAG, UAA and UGA