Connective Tissue Flashcards
What roles are played by connective tissue?
Protection
Storage of energy supplies
Support
What describes collagen fibres?
A TRIPLE helix of fibrous collagen protein
Which amino acid is found at every 3rd position in collagen?
Glycine!
The most common form of collagen found in the basement membrane is…
Type IV
What are the MAJOR materials packed around the collagen fibres in the extra cellular matrix?
Glycosaminoglycans
The type of tissue that contains a fluid known as the ‘Ground Substance’ is…
Connective / supportive
Adhesion proteins link components of the … together and link … to the …
Elastic fibres return to their … shape after …
Glycoaminoglycans (GAGs) provide … and retain …
Collagen fibres provide …
ECM, cells, ECM
Original, distorting
Support, water
Strength
Name 3 types of cell found in the connective tissue.
Fibroblast
Osteoblast
Chondrocyte
Where you find loose connective tissue?
Where would you find dense?
Under skin
Tendons
Name the 2 processes by which cartilage grows.
Appositional
Interstitial
Fibrocartilage is found attaching … to bone and in … discs.
Hyaline cartilage is found in the … of … bones and the … in developing …
Elastic cartilage is found in the … and …
Tendon, vertebral
Growing point, long, Skeleton, foetus
Ear, epiglottis
Osteoclasts are involved in …
Bone reabsorption
Osteoblasts are found in…
Cells at the growing surface, secreting ECM
Osteocytes are involved in…
Bone maintenance + are found in cells within bone ECM
Osteoids are found in the…
Extracellular Matrix of bone
What is involved in bone reabsorption?
Secretion of acid
Secretion of lysosomal enzymes
Transcytosis
Blood cells are derived from…
Mesenchyme
Blood consists of 2 components. The fluid stroma or plasma consists MAINLY of…
Water!
Macrophages are linked to the … of bacteria.
Platelets are involved in…
Erythrocytes carry…
B-lymphocytes make…
Phagocytosis
Blood clotting
Oxygen
Antibodies
Roles of connective tissue?
Structural framework Transporting fluids + dissolved material Protecting delicate organs Storing energy reserves Defending body from microorganisms!
Elastic fibres have a high elasticity and enable organs to stretch + return to original shape.
Examples of where they’re found?
Skin, arteries, lung, intestine, bladder, heart.
Describe process of Interstitial Bone Growth.
Lengthens bones) (Occurs at epiphyseal plate!
Chondrocytes are cells that can produce cartilage.
They will divide and produce daughter cells = additional cartilage! This can then be mineralised to lengthen bone.
This starts in embryonic development and continues to adolescence. KEY for development!
Describe the process of Appositional Bone Growth.
Bone remodelling) (increases bone density) (also occurs due to trauma, to repair bone!
Under the surface, chondrocytes are activated.
The perichondrium on the outside divides repeatedly to become chondroblasts (immature chondrocytes).
These mature and produce cartilage, are embedded in the matrix to cause further bone growth / remodelling.
Which part of the embryo does connective tissue derive from?
The Mesoderm
What is NOT a role of connective tissue?
Conducts electrical impulses
Which cell synthesises collagen?
Fibroblast
Which cell makes bone extracellular matrix?
Osteoblast
What does NOT contain specialised dense connective tissue?
Tongue (contains generalised)
Cartilage is made up of GAGs and…
Collagen Type 2
