Rheumatology Flashcards

1
Q

What are features of septic arthritis?

A
Acute onset of fever
Joint pain and swelling
Ill appearance
Irritable
Tachycardia
Joint eddusion
Periarticular warmth and tenderness
Pain on movement
Any age
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2
Q

What are investigations for septic arthritis?

A
Very high CRP and ESR
Raised WCC
High platelets
Blood cultures taken but results are negative
Ultrasound may show effusion
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3
Q

How is septic arthritis managed?

A

Referral to orthopaedics
Empirical broad spectrum IV antibiotics
Joint aspiration - help child move joint by reducing fluid and also microscopy and culture to determine causative organism

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4
Q

What are features of Slipped Upper Femoral Epiphysis?

A
Displacement of the capital femoral epiphysis from femoral neck
Most common hip disorder in adolescence
Associated with obesity
Pain and altered gait
Worse with activity
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5
Q

What is the main feature of SUFE Xray?

A

‘Ice cream slipping off cone’

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6
Q

How is SUFE managed?

A

Referral to orthopaedicss

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7
Q

What are features of transient synovitis?

A
Pain and limited movement in hips
Relatively common
Unclear aetiology
3-8 years age group
Symptoms<1 week
Fever absent or low grade
Not unwell looking
Bilateral effusion on ultrasound
Resolve gradually with conservative therapy - analgesia
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8
Q

What are features of perthes?

A
Idiopathic avascular necrosis of hip joint
Presents as insidious hip pain and limp
Pain not relieved by rest or medication
3-12 years
Males more common - 3.5:1
Undefined aetiology
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9
Q

How is perthes managed?

A

Minimal weight bearing
Contain head within acetabulum with use of splints
Occassional surgery
Refer to orthopaedics

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10
Q

What determines outcome of perthes

A

Age at onset - Younger better outcome

Depends on degree of involvement of femoral head

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11
Q

What are potential causes of JIA?

A
Genetic susceptibility
Immune response
Pro-inflammatory markers
Presence antibodies
Ongoing research
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12
Q

What are symptoms of JIA?

A
Arthritis for at least 6 weeks
Morning stiffness or gelling
Refusal to walk in toddlers
School absence or limited ability to participate in physical activity
Rash/fever
Fatigue
Poor appetite/weight loss
Delayed puberty
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13
Q

What are different types of JIA?

A
Oligoarthritis
Polyarthritis (Rheumatoid factor + or -)
Enthesitis related arthritis - tendons
Psoriatic arthritis - related to psoriasis
Systemic onset JIA
Undifferentiated arthritis
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14
Q

What are signs of JIA?

A
Swelling
Tensosynovitis
Pain
Joint held in position of maximum comfort
Range of motion limited at extremes
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15
Q

What are features of systemic JIA?

A
Unwell
Arthritis
Intermittent fever >2 weeks
Salmon pink erythematous rash
Generalised lymphadenopathy
Serositis
Hepatomegaly/splenomegaly
High inflammatory markers - ESR and CRP
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16
Q

How is the specific type of arthritis diagnosed?

A

History
Physical examination and findings
Investigations

17
Q

What investigations?

A

Labs - WCC, CRP, ESR,
Plain Xray
USS
MRI with contrast

18
Q

What are goals of treatment for arthritis?

A
Pharmaological management consisting of NSAIDs, DMARDs, biologics, and intra-articular/oral steroids
Nutrition
Physio
Return to school
Occupational therapy
19
Q

What is the DMARD of choice?

A

Methotrexate

20
Q

What are features od DMARDs for JIA?

A

Used when steroids don’t work in oligo JIA

Used early for good outcome

21
Q

What is the most common associated symptom of JIA?

A

Uveitis

22
Q

What are features of uveitis in JIA?

A
Untreated leads to chronic
Screening in all JIA patients
<5 years
Rarely symptomatic 
Red eyes, headache, reduced vision
If not treated cataracts, glaucoma
23
Q

How is uveitis treated?

A

Topical steroids to reduce inflammation

DMARDs and biologics if poor response to steroids

24
Q

What are complications of JIA?

A
Poor growth
Osteopenia
Localised growth disturbances - leg length discrepancy
Micrognathia
Contractures
Ocular complications