Rheumatology Flashcards
Pneumonic for possible SLE symptoms?
MD SOAP BRAIN
List some possible SLE symptoms?
MD SOAP BRAIN
- Malar/Discoid rash
- Serositis - chest pain
- Oral ulcers
- Arthritis
- Photosensitivity
- Blood - anemia
- Renal failure
- ANA (+)
- Immunologic
- Neuro = cerebritis
List some possible SLE symptoms?
MD SOAP BRAIN
- Malar/Discoid rash
- Serositis
- Oral ulcers
- Arthritis
- Photosensitivity
- Bleeding - anemia
- Renal failure
- ANA (+)
- Immunologic
- Neuro - cerebritis
What are 4 possible antibodies seen with SLE?
ANA
dsDNA
Anti-Smith
Anti-Histone
Levels of ESR/CRP and C3/C4 with SLE?
ESR/CRP = High
C3/C4 = LOW
What is the treatment for SLE?
Hydroxychloroquine +/- steroids during flare
What are 3 possible medicines that commonly cause Drug-Induced SLE?
Hydralazine
Procainamide
Alpha-Methyldopa
What specific antibody is often positive with Drug-Induced SLE?
Anti-Histone
Treatment for Drug-Induced SLE?
Discontinue causative medication
With SLE, it can commonly cause Renal manifestations. What is the treatment?
IV Cyclophosphamide
With SLE, it can commonly cause Renal manifestations. What is the treatment?
IV Cyclophosphamide
Where will the RA present?
Smaller joints - hands/feet and SYMMETRIC!
If the ____ joint is involved… it is NOT RA
DIP
Common characteristic of pain with RA?
Long-lasting morning stiffness
What is the most specific marker for RA?
Anti-CCP is more specific than RF
What will be seen on X-ray with RA?
Erosions/Periarticular Osteopenia
– Due to pannus formation which erodes bone
1st and 2nd line drugs to treat RA?
- Methotrexate
- Leflunomide
1st and 2nd line drugs to treat RA?
- Methotrexate
- Leflunomide
3 common side effects of Methotrexate?
- Liver toxicity
- Oral ulcers
- Macrocytic anemia
How do you offset Methotrexate adverse effects?
Give folic acid
What antibody is usually positive with Limited Scleroderma?
Anti-Centromere
Pneumonic for Scleroderma symptoms?
CREST