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COMAT - IM > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

Pneumonic for possible SLE symptoms?

A

MD SOAP BRAIN

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2
Q

List some possible SLE symptoms?

A

MD SOAP BRAIN
- Malar/Discoid rash
- Serositis - chest pain
- Oral ulcers
- Arthritis
- Photosensitivity
- Blood - anemia
- Renal failure
- ANA (+)
- Immunologic
- Neuro = cerebritis

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3
Q

List some possible SLE symptoms?

A

MD SOAP BRAIN
- Malar/Discoid rash
- Serositis
- Oral ulcers
- Arthritis
- Photosensitivity
- Bleeding - anemia
- Renal failure
- ANA (+)
- Immunologic
- Neuro - cerebritis

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4
Q

What are 4 possible antibodies seen with SLE?

A

ANA
dsDNA
Anti-Smith
Anti-Histone

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5
Q

Levels of ESR/CRP and C3/C4 with SLE?

A

ESR/CRP = High
C3/C4 = LOW

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6
Q

What is the treatment for SLE?

A

Hydroxychloroquine +/- steroids during flare

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7
Q

What are 3 possible medicines that commonly cause Drug-Induced SLE?

A

Hydralazine
Procainamide
Alpha-Methyldopa

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8
Q

What specific antibody is often positive with Drug-Induced SLE?

A

Anti-Histone

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9
Q

Treatment for Drug-Induced SLE?

A

Discontinue causative medication

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10
Q

With SLE, it can commonly cause Renal manifestations. What is the treatment?

A

IV Cyclophosphamide

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11
Q

With SLE, it can commonly cause Renal manifestations. What is the treatment?

A

IV Cyclophosphamide

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12
Q

Where will the RA present?

A

Smaller joints - hands/feet and SYMMETRIC!

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13
Q

If the ____ joint is involved… it is NOT RA

A

DIP

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14
Q

Common characteristic of pain with RA?

A

Long-lasting morning stiffness

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15
Q

What is the most specific marker for RA?

A

Anti-CCP is more specific than RF

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16
Q

What will be seen on X-ray with RA?

A

Erosions/Periarticular Osteopenia
– Due to pannus formation which erodes bone

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17
Q

1st and 2nd line drugs to treat RA?

A
  1. Methotrexate
  2. Leflunomide
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18
Q

1st and 2nd line drugs to treat RA?

A
  1. Methotrexate
  2. Leflunomide
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19
Q

3 common side effects of Methotrexate?

A
  1. Liver toxicity
  2. Oral ulcers
  3. Macrocytic anemia
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20
Q

How do you offset Methotrexate adverse effects?

A

Give folic acid

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21
Q

What antibody is usually positive with Limited Scleroderma?

A

Anti-Centromere

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22
Q

Pneumonic for Scleroderma symptoms?

A

CREST

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23
Q

What are some symptoms seen with Limited Scleroderma?

A

CREST
- Calcinosis
- Raynaud’s
- Esophageal motility
- Sclerodactyly
- Telangiectasias

24
Q

How does Diffuse Scleroderma differ from Limited Scleroderma?

A

Diffuse = CREST + visceral involvement

25
Q

What antibody is often positive with Diffuse Scleroderma?

A

Anti- scl 70 Topoisomerase

26
Q

What is the treatment for Scleroderma?

A

Supportive

27
Q

What complication can occur with Scleroderma?

A

Pulmonary HTN

28
Q

What are 2 possible signs of Diffuse Scleroderma in addition to CREST?

A

ILD
Constrictive Pericarditis

29
Q

What causes Sjogren’s Syndrome?

A

Lymphoplasmacytic exocrine gland destruction

30
Q

3 signs of Sjogren’s Syndrome?

A

Dry eyes
Dry mouth
Parotid swelling

31
Q

3 signs of Sjogren’s Syndrome?

A

Dry eyes
Dry mouth
Parotid swelling

32
Q

What antibody will be positive with Sjogren’s?

A

Anti-RO/LA

33
Q

Treatment for Sjogren’s?

A

Artificial tears/saliva

34
Q

With the inflammatory myopathies (dermatomyositis/polymyositis//ibm), what are the signs?

A

Proximal muscle weakness
Derm findings

35
Q

List 3 possible derm findings for the inflammatory myopathies (dermatomyositis/polymyositis/ibm)?

A

Heliotrope rash = purple around eyes
Gottran’s papules
Shawl sign = skin exposed to sun gets rash

36
Q

What marker is often elevated with the inflammatory myopathies? What are 2 possible positive antibodies?

A

HIGH CK
(+) Anti-mi and (+) Anti-Jo

37
Q

How will Pseudogout look on arthrocentesis?

A

Positively birefringent rhomboid crystals of calcium-phosphate

38
Q

How will Gout look on arthrocentesis?

A

Negatively birefringent needles of monosodium urate

39
Q

What is the treatment for Gout/Pseudogout flares?

A

Colchicine or NSAIDs

40
Q

2 treatment options for chronic gout?

A

Allopurinol
Probenecid if under excreter

41
Q

How will Ankylosing Spondylitis present?

A

Low back pain that is worse in the morning
= Sacroiliitis

42
Q

How will the spine look with Ankylosing Spondylitis?

A

“Bamboo spine”

43
Q

What can be seen with Psoriatic Arthritis?

A
  • Arthritis
  • Psoriasis
  • Nail pitting
44
Q

What can be seen with Reactive Arthritis?

A
  • Urethritis
  • Conjunctivitis
  • Arthritis
45
Q

What are 4 seronegative but HLA-B27 diseases?

A
  1. Ankylosing Spondylitis
  2. Psoriatic Arthritis
  3. Reactive Arthritis
  4. IBD-Related
46
Q

Describe how Complex Regional Pain Syndrome will present?

A

Trauma/injury –> Heals
–> Burning pain, swelling, redness, loss of ROM

47
Q

Burning pain with swelling, erythema, etc. following trauma to a region is?

A

Complex Regional Pain Syndrome

48
Q

What can be seen on X-ray of the region affected with Complex Regional Pain Syndrome?

A

Demineralization/Osteopenia

49
Q

If you diagnose a patient with an inflammatory myopathy like Dermatomyositis, what should you do next?

A

Screen for malignancies!!

50
Q

What pathology in the cervical spine are patient’s with RA at risk for?

A

AA subluxation

51
Q

What will you see with Polymyalgia Rheumatica?

A

Proximal muscle stiffness/pain
+ HIGH ESR/CRP

52
Q

If you see proximal muscle stiffness/pain with elevated inflammatory markers, what is the likely diagnosis?

A

Polymyalgia Rheumatica

53
Q

What is the treatment for Polymyalgia Rheumatica?

54
Q

What is Polymyalgia Rheumatic often associated with?

A

Giant Cell Arteritis

55
Q

What is a possible adverse effect of SLE patients taking Hydroxychloroquine?

A

Retinopathy/vision loss

COMAT - IM (17 decks)

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