CAD/ACS Flashcards
What are the indications for a CABG?
- LAD is affected
- 3 vessel disease
- 2 vessel disease if a diabetic
- Symptomatic despite maximal therapy
What is the physiology behind angina?
Oxygen supply cannot meet the demand of the heart!
Describe how stable angina will present?
Exertion/stress
–> Chest pain
–> Relieved by rest or nitrates
Describe how stable angina will present?
Exertion/stress
–> Chest pain
–> Relieved by rest or nitrates
Can you have other symptoms such as diaphoresis, SOB, dizziness, N/V with stable angina?
YES
What will the results of the EKG and Cardiac Enzymes be with Stable Angina? Unstable Angina?
NEGATIVE
What defines Unstable Angina?
- Chest pain now occurring at rest
- Chest pain that is worsening in nature, such that is occurs easier, lasts longer, etc.
What defines Unstable Angina?
- Chest pain now occurring at rest
- Chest pain that is worsening in nature, such that it occurs easier, lasts longer, etc.
Besides EKG and Cardiac Enzymes, what are 2 other tests that can be done to assess coronary vasculature?
- Stress testing
- Coronary angiography
With stress testing is is either with exertion or?
Medication such as Dobutamine
With stress testing with medications, how does that work?
Diseased vessels are already maximally dilated so change will be seen in the non-diseased vessels
Prior to a stress test, what medications should be held for at least 48 hours? (3)
Beta blockers
CCBs
Nitrates
What is the mainstay of treatment for Stable Angina?
Aspirin
Beta blockers
+/- Nitroglycerin
What causes Prinzmetal Angina?
Coronary vessel vasospasm
How will Prinzmetal Angina present? In who?
Young women with chest pain that occurs at rest and often in the morning
How will Prinzmetal Angina present? In who?
Young women with chest pain that occurs at rest and often in the morning
What is the best treatment for Prinzmetal Angina?
CCBs!
Results of the EKG and Cardiac Enzymes for a NSTEMI?
EKG = normal
Cardiac enzymes = (+)
What is the full treatment for ACS?
MONA-B(ASH)
- Morphine
- O2
- Nitrates
- Aspirin + other Anti-platelets
- Beta blocker
- ACEi
- Statin
- Heparin
What is the full treatment for ACS?
MONA-BASH
- Morphine
- O2
- Nitrate
- Aspirin + Antiplatelet therapies
- Beta-blocker
- ACEi
- Statin
- Heparin
With a STEMI what can show up on an EKG? (4)
ST elevations
NEW LBBB
+/- Q waves and T wave inversions
When do Troponins and CK-MB peak?
Troponins = 24-48 hours
CK-MB = Within 24 hours
In what leads will an Inferior MI present? Vessel?
Leads II, III, AVF
= Right Coronary A.
What medications should you avoid if you suspect an Inferior MI and why?
Nitrates because it will drop the BP since the RV is affected
In what leads will an Anterior MI present? Vessel?
V1 - V4
= Left Anterior Descending
In what leads will a Lateral MI present? Vessel?
Leads I, AVL, V5, V6
= Left Circumflex A.
In what leads will a Posterior MI present? What will you see?
ST depression in V1 and V2
IF PCI cannot be performed in less than ____ and theres no contraindications, administer _____
< 120 mins
Give Thrombolytics = tPa, reteplase, streptokinase…
Day 1 following an MI, what are you worried about?
Heart failure
Days 2-4 following an MI, what are you worried about? (2)
Arrhythmias
Pericarditis
Days 2-4 following an MI, what are you worried about? (2)
Arrhythmias
Pericarditis
Days 5-10 following an MI, what are you worried about (3)?
LV wall rupture
Papillary muscle rupture
Septal rupture
Days 5-10 following an MI, what are you worried about? (3)
LV wall rupture
Papillary muscle rupture
Septal rupture
If LV wall ruptures, how will that present?
Like cardiac tamponade!
If a papillary muscle ruptures, how will that present?
Pulmonary edema
Mitral regurgitation
If the septum ruptures, how will that present?
Increased oxygen in the RV
In the weeks to months following an MI, what are you worried about?
Ventricular aneurysm
In the weeks to months following an MI, what are you worried about?
Ventricular aneurysm
For Peripheral Arterial Disease, what are 3 mainstays of treatment not including Cilostazol?
Aspirin
Statin
Exercise therapy
How does Cardiac Tamponade arise?
- Fluid in pericardial sac
- Increases the intracardial pressure
- Decreased filling of the heart
= Decreased CO
What will be present with Cardiac Tamponade?
JVD
Distant heart sounds
Hypotension
Pulsus Paradoxus
What will be seen on EKG with Cardiac Tamponade?
Electrical alternans
What will be seen on Echo with Cardiac Tamponade?
RA and RV collapse
What virus commonly causes Pericarditis?
Coxsackie B
If Pericarditis occurs following an MI, what is the likely cause?
Autoimmune = Dressler syndrome
How will Pericarditis present?
Pleuritic chest pain and dyspnea
+/- cough and fever
What will make the pain BETTER with Pericarditis?
Sitting up and bending forward
What may you hear on Auscultation with Pericarditis?
Friction rub throughout heart sounds
what will be seen on EKG with Pericarditis? (2 options)?
DIFFUSE ST elevation
DIFFUSE PR depression
What is the treatment for Pericarditis?
Aspirin/NSAIDs + Colchicine
+/- Steroids