Rheumatoid Arthritis Flashcards

0
Q

Percentage of RA patients with negative RF

A

30%

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1
Q

The “shared epitope” refers to an amino acid sequence shared by these (3) HLA-DRB chains and is a strong risk factor for RA

A

DR4, DR14, DR1

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2
Q

Percentage of RA patients with negative anti-CCP

A

40%

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3
Q

Strong environmental risk factor for developing RA

A

Smoking

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4
Q

Occupational exposures linked to RA

A

Asbestos and silica

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5
Q

Marginal erosions in RA may be evident earliest at this joint

A

5th MTP

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6
Q

Joints spared in RA

A

DIP, lumbar spine

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7
Q

Most common entrapment neuropathy in RA

A

Carpal tunnel syndrome

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8
Q

Condition where RF has 100% sensitivity

A

Mixed cryoglobulinemia

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9
Q

Percentage of Sjögren syndrome patients with a positive RF

A

70%

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10
Q

Percentage of SLE patients with positive RF

A

20-30%

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11
Q

The “shared epitope” refers to an amino acid shared by these (3) HLA-DRB chains and is a strong risk factor for RA

A

DR4, DR14, DR1

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12
Q

Percentage of RA patients with negative RF

A

30%

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13
Q

Percentage of RA patients with negative anti-CCP

A

40%

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14
Q

Strong environmental risk factor for developing RA

A

Smoking

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15
Q

Occupational exposures linked to RA

A

Asbestos and silica

16
Q

Marginal erosions in RA may be evident earliest at this joint

A

5th MTP

17
Q

Joints spared in RA

A

DIP, lumbar spine

18
Q

Most common entrapment neuropathy in RA

A

Carpal tunnel syndrome

19
Q

Condition where RF has 100% sensitivity

A

Mixed cryoglobulinemia

20
Q

Percentage of Sjögren syndrome patients with a positive RF

A

70%

21
Q

Percentage of SLE patients with positive RF

A

20-30%

22
Q

The “shared epitope” refers to an amino acid shared by these (3) HLA-DRB chains and is a strong risk factor for RA

A

DR4, DR14, DR1

23
Q

Percentage of RA patients with negative RF

A

30%

24
Q

Percentage of RA patients with negative anti-CCP

A

40%

25
Q

Strong environmental risk factor for developing RA

A

Smoking

26
Q

Occupational exposures linked to RA

A

Asbestos and silica

27
Q

Marginal erosions in RA may be evident earliest at this joint

A

5th MTP

28
Q

Joints spared in RA

A

DIP, lumbar spine

29
Q

Most common entrapment neuropathy in RA

A

Carpal tunnel syndrome

30
Q

Condition where RF has 100% sensitivity

A

Mixed cryoglobulinemia

31
Q

Percentage of Sjögren syndrome patients with a positive RF

A

70%

32
Q

Percentage of SLE patients with positive RF

A

20-30%

33
Q

Specificity of anti-CCP in RA

A

95%

34
Q

Specificity of RF in RA

A

80%

35
Q

Components of Felty syndrome

A

RA
Pancytopenia
Splenomegaly
Leg ulcers

36
Q

Biologic DMARD used for RA that is associated with an increased risk of lymphoma, lung cancer, and COPD flares

A

Abatacept

37
Q

Patients with RA may be more likely to respond to rituximab if they are positive for this serology

A

RF