Rheumatoid Arthritis Flashcards
Percentage of RA patients with negative RF
30%
The “shared epitope” refers to an amino acid sequence shared by these (3) HLA-DRB chains and is a strong risk factor for RA
DR4, DR14, DR1
Percentage of RA patients with negative anti-CCP
40%
Strong environmental risk factor for developing RA
Smoking
Occupational exposures linked to RA
Asbestos and silica
Marginal erosions in RA may be evident earliest at this joint
5th MTP
Joints spared in RA
DIP, lumbar spine
Most common entrapment neuropathy in RA
Carpal tunnel syndrome
Condition where RF has 100% sensitivity
Mixed cryoglobulinemia
Percentage of Sjögren syndrome patients with a positive RF
70%
Percentage of SLE patients with positive RF
20-30%
The “shared epitope” refers to an amino acid shared by these (3) HLA-DRB chains and is a strong risk factor for RA
DR4, DR14, DR1
Percentage of RA patients with negative RF
30%
Percentage of RA patients with negative anti-CCP
40%
Strong environmental risk factor for developing RA
Smoking