Rheumatoid Arthritis Flashcards

0
Q

Percentage of RA patients with negative RF

A

30%

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1
Q

The “shared epitope” refers to an amino acid sequence shared by these (3) HLA-DRB chains and is a strong risk factor for RA

A

DR4, DR14, DR1

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2
Q

Percentage of RA patients with negative anti-CCP

A

40%

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3
Q

Strong environmental risk factor for developing RA

A

Smoking

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4
Q

Occupational exposures linked to RA

A

Asbestos and silica

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5
Q

Marginal erosions in RA may be evident earliest at this joint

A

5th MTP

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6
Q

Joints spared in RA

A

DIP, lumbar spine

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7
Q

Most common entrapment neuropathy in RA

A

Carpal tunnel syndrome

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8
Q

Condition where RF has 100% sensitivity

A

Mixed cryoglobulinemia

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9
Q

Percentage of Sjögren syndrome patients with a positive RF

A

70%

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10
Q

Percentage of SLE patients with positive RF

A

20-30%

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11
Q

The “shared epitope” refers to an amino acid shared by these (3) HLA-DRB chains and is a strong risk factor for RA

A

DR4, DR14, DR1

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12
Q

Percentage of RA patients with negative RF

A

30%

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13
Q

Percentage of RA patients with negative anti-CCP

A

40%

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14
Q

Strong environmental risk factor for developing RA

A

Smoking

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15
Q

Occupational exposures linked to RA

A

Asbestos and silica

16
Q

Marginal erosions in RA may be evident earliest at this joint

17
Q

Joints spared in RA

A

DIP, lumbar spine

18
Q

Most common entrapment neuropathy in RA

A

Carpal tunnel syndrome

19
Q

Condition where RF has 100% sensitivity

A

Mixed cryoglobulinemia

20
Q

Percentage of Sjögren syndrome patients with a positive RF

21
Q

Percentage of SLE patients with positive RF

22
Q

The “shared epitope” refers to an amino acid shared by these (3) HLA-DRB chains and is a strong risk factor for RA

A

DR4, DR14, DR1

23
Q

Percentage of RA patients with negative RF

24
Percentage of RA patients with negative anti-CCP
40%
25
Strong environmental risk factor for developing RA
Smoking
26
Occupational exposures linked to RA
Asbestos and silica
27
Marginal erosions in RA may be evident earliest at this joint
5th MTP
28
Joints spared in RA
DIP, lumbar spine
29
Most common entrapment neuropathy in RA
Carpal tunnel syndrome
30
Condition where RF has 100% sensitivity
Mixed cryoglobulinemia
31
Percentage of Sjögren syndrome patients with a positive RF
70%
32
Percentage of SLE patients with positive RF
20-30%
33
Specificity of anti-CCP in RA
95%
34
Specificity of RF in RA
80%
35
Components of Felty syndrome
RA Pancytopenia Splenomegaly Leg ulcers
36
Biologic DMARD used for RA that is associated with an increased risk of lymphoma, lung cancer, and COPD flares
Abatacept
37
Patients with RA may be more likely to respond to rituximab if they are positive for this serology
RF