Rheumatoid Arthritis Flashcards
1
Q
Methotrexate SE
DMARD
A
Pneumonitis
Mouth ulcers/mucositis
Liver toxicity
BMS
Teratogenic
2
Q
Hydroxychloroquine SE
DMARD
A
Retinal toxicity —> permanent VI
Blue-grey skin pigmentation
Hair lightening
Renal and liver impairment
3
Q
Infliximab SE
Anti-TNFa
A
Reactivation of Hep B/TB
Drug induced lupus/vitiligo/psoriasiform lesions
Blood dyscrasias
Monitor signs of infection
4
Q
Sulfasalazine SE
- DMARD*
A
BMS
Folate def./megaloblastic anaemia
Orange urine
Reduced sperm count
Insomnia
Altered taste
Haemolytic anaemia in G6PD def.
5
Q
Leflunomide SE
- DMARD*
A
HTN
Peripheral neuropathy
Mouth ulcers/mucositis
BMS
Liver toxicity
teratogenic
Monitor wt + ht
6
Q
Penicillamine SE
DMARD
A
Nephrotic syndrome
Immune-mediated nephropathy
7
Q
Rituximab SE
Anti-CD20 on B cells
A
Night sweats
⬇️plts
